梅毒患者治疗未完成的风险因素。
Risk factors for treatment non-completion among patients with syphilis.
作者信息
Clarkson-During Abigail, Almirol Ellen, Eller Dylan, Hazra Aniruddha, Stanford Kimberly A
机构信息
Section of Emergency Medicine, The University of Chicago, Chicago, IL, USA.
Section of Infectious Diseases and Global Health, The University of Chicago, Chicago, IL, USA.
出版信息
Ther Adv Infect Dis. 2024 Jul 30;11:20499361241265941. doi: 10.1177/20499361241265941. eCollection 2024 Jan-Dec.
BACKGROUND
With recent increases in syphilis, there is growing interest in expanding screening; however, treatment rates have historically been low.
OBJECTIVES
This study examines demographic and clinical factors that may contribute to non-completion of syphilis treatment.
DESIGN
This is a retrospective comparative cohort study of all patients with syphilis from January through November 2018 at an urban, tertiary care hospital.
METHODS
Demographics and clinical information were extracted from the electronic medical record. Descriptive statistics and odds ratios (ORs) were calculated.
RESULTS
Of 171 patients with syphilis, 89 (52.0%) completed treatment. Patients ages 40-49 were least likely to complete treatment (OR 0.14; 95% CI 0.03-0.72, = 0.02) compared to those ages 18-24. Non-heterosexual patients were significantly more likely to complete treatment (OR 3.60; 95% CI 1.13-11.49, = 0.03) compared to heterosexual patients. Patients diagnosed in the emergency department completed treatment at the lowest rate.
CONCLUSION
A major gap in syphilis treatment still exists, which must be addressed to achieve optimal impact from syphilis screening programs.
背景
随着近期梅毒发病率的上升，扩大筛查的关注度日益增加；然而，历史上治疗率一直较低。
目的
本研究调查可能导致梅毒治疗未完成的人口统计学和临床因素。
设计
这是一项对2018年1月至11月在一家城市三级护理医院的所有梅毒患者进行的回顾性比较队列研究。
方法
从电子病历中提取人口统计学和临床信息。计算描述性统计量和比值比（OR）。
结果
在171例梅毒患者中，89例（52.0%）完成了治疗。与18 - 24岁的患者相比，40 - 49岁的患者完成治疗的可能性最小（OR 0.14；95% CI 0.03 - 0.72，P = 0.02）。与异性恋患者相比，非异性恋患者完成治疗的可能性显著更高（OR 3.60；95% CI 1.13 - 11.49，P = 0.03）。在急诊科确诊的患者完成治疗的比例最低。
结论
梅毒治疗中仍存在重大差距，必须加以解决，以便梅毒筛查项目能产生最佳效果。
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