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[马来酸衍生物的放射增敏活性。马来酸邻硝基苯胺、苯胺和二乙酯对经γ射线辐照的大肠杆菌B/r细胞存活的影响]

[Radiosensitizing activity of maleic acid derivatives. Effect of maleic acid o-nitroanilide, anilide and diethyl ester on the survival of gamma-irradiated cells of Escherichia coli B/r].

作者信息

Riabchenko N I, Proskuriakov S Ia, Petrova K M, Riabchenko V I, Trofimov F A

出版信息

Radiobiologiia. 1985 Nov-Dec;25(6):795-8.

PMID:3909213
Abstract

Among three substances under study, only o-nitroanilide of maleic acid (oNAM) possessed a radiosensitizing activity. Radiosensitivity of E. coli B/r cells irradiated in the presence of Ar and oNAM was higher by 4.8 times than that of irradiated controls. The survival rate of E. coli B/r cells irradiated in the presence of oxygen was changed by 1.4 times by the effect of oNAM.

摘要

在所研究的三种物质中，只有马来酸邻硝基苯胺（oNAM）具有放射增敏活性。在氩气和oNAM存在下辐照的大肠杆菌B/r细胞的放射敏感性比辐照对照组高4.8倍。在氧气存在下辐照的大肠杆菌B/r细胞的存活率因oNAM的作用而改变了1.4倍。

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