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同种异体骨软骨移植联合同侧外踝骨软骨移植治疗距骨内侧骨软骨损伤的疗效。

Outcomes of Osteochondral Autologous Transplantation with Ipsilateral Lateral Talar Autograft for Medial Osteochondral Lesions of the Talus.

机构信息

Department of Orthopedic Surgery, Dankook University College of Medicine, Cheonan, Korea.

出版信息

Clin Orthop Surg. 2024 Aug;16(4):620-627. doi: 10.4055/cios23327. Epub 2024 Apr 25.

Abstract

BACKGROUND

Osteochondral autologous transplantation (OAT) has been widely used in the treatment of osteochondral lesion of the talus (OLT). Previous studies have reported successful outcomes following the use of osteochondral autogenous grafts from the intercondylar notch of the knee or a non-weight-bearing region of the femoral condyle. However, donor-site morbidity of the knee joint has been observed in several cases. This study aimed to investigate the outcomes and safety of OAT with autografts from the ipsilateral lateral talar articular facet as an alternative donor site for medial OLT.

METHODS

Among 40 patients who underwent OAT, 29 patients were excluded. Eleven patients who underwent OAT with an osteochondral graft harvested from the ipsilateral lateral talar articular facet from 2011 to 2022 were retrospectively analyzed. The size of OLT was measured on ankle magnetic resonance imaging, including coronal length, sagittal length, depth, and area. Clinical outcomes were evaluated using the American Orthopaedic Foot and Ankle Society (AOFAS) ankle-hindfoot scale and a visual analog scale (VAS). Weight-bearing ankle radiographs were obtained postoperatively and at 1 year after surgery.

RESULTS

The average follow-up time after surgery was 64.7 months (range, 14-137 months). The average diameter of lesions was 8.8 mm (range, 8-9.9 mm). The average size of lesions was 51.2 mm (range, 33.6-71.3 mm) , and all lesions included subchondral cysts. The average depth of lesions was 7.3 mm (range, 6.2-9.1 mm). Graft sizes ranged from 8 to 10 mm in diameter (8 mm, n = 1; 10 mm, n = 10) All measured clinical outcomes improved postoperatively, including the AOFAS scores (preoperative, 55.4 ± 9.0; 1-year follow-up, 92.1 ± 7.6; = 0.001) and VAS scores (preoperative, 5.5 ± 0.7; 1-year follow-up, 1.9 ± 0.8; = 0.001). All weight-bearing ankle radiographs of the graft and donor sites did not reveal arthritic change in the ankle joint, lateral talar dome collapse, and graft-site delayed union or nonunion at 1 year after surgery.

CONCLUSIONS

For a single medial OLT, harvesting autografts from the ipsilateral lateral talar articular facet without knee donor-site morbidities can be a good alternative in OAT for OLT.

摘要

背景

骨软骨自体移植(OAT)已广泛应用于距骨骨软骨病变(OLT)的治疗。既往研究报道,取自膝关节髁间窝或股骨髁非负重区的骨软骨自体移植物可获得成功的结果。然而,在一些病例中观察到了膝关节供区的发病率。本研究旨在探讨采用同侧外侧距骨关节面作为内侧 OLT 供区的自体移植物进行 OAT 的结果和安全性。

方法

在接受 OAT 的 40 例患者中,排除了 29 例患者。回顾性分析了 2011 年至 2022 年期间,11 例接受了取自同侧外侧距骨关节面的骨软骨移植物的 OAT 患者。OLT 的大小在踝关节磁共振成像上进行测量,包括冠状长度、矢状长度、深度和面积。采用美国矫形足踝协会(AOFAS)踝关节-后足量表和视觉模拟量表(VAS)评估临床结果。术后和术后 1 年拍摄负重踝关节 X 线片。

结果

术后平均随访时间为 64.7 个月(范围,14-137 个月)。病变平均直径为 8.8 毫米(范围,8-9.9 毫米)。病变平均大小为 51.2 毫米(范围,33.6-71.3 毫米),所有病变均包含软骨下囊肿。病变平均深度为 7.3 毫米(范围,6.2-9.1 毫米)。移植物直径为 8-10 毫米(8 毫米,n=1;10 毫米,n=10)。所有测量的临床结果均在术后得到改善,包括 AOFAS 评分(术前,55.4±9.0;术后 1 年随访,92.1±7.6; =0.001)和 VAS 评分(术前,5.5±0.7;术后 1 年随访,1.9±0.8; =0.001)。术后 1 年,所有负重踝关节 X 线片均未显示踝关节关节炎、外侧距骨穹窿塌陷以及移植物部位延迟愈合或不愈合。

结论

对于单个内侧 OLT,取自同侧外侧距骨关节面的自体移植物,避免了膝关节供区的发病率,是 OLT 的 OAT 的一个很好的选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a53/11262937/33576395b517/cios-16-620-g001.jpg

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