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伪装成心力衰竭的免疫触须样肾小球病。

Immunotactoid Glomerulopathy Masquerading as Heart Failure.

作者信息

Ali Kabeer, Agrawal Avni, Karan Abhinav, Marsalisi Christopher, O'Brien Melville C, Liu Shiguang, Jaikaransingh Vishal

机构信息

Internal Medicine, University of Florida College of Medicine, Jacksonville, USA.

Pathology and Laboratory Medicine, University of Florida College of Medicine, Jacksonville, USA.

出版信息

Cureus. 2024 Jul 2;16(7):e63687. doi: 10.7759/cureus.63687. eCollection 2024 Jul.

Abstract

Immunotactoid glomerulopathy (ITG) is a rare form of glomerular disease. It is characterized by organized, dense immunoglobulin deposits in the glomerulus, impairing glomerular function and filtration. The prognosis tends to be poor, and the majority of patients develop end-stage renal disease (ESRD). Here, we present a case of a young male with no prior medical history who presented with anasarca. His presentation was initially thought to be due to a new diagnosis of heart failure with a decreased ejection fraction. However, significant proteinuria led to a diagnosis of ITG.

摘要

免疫触须样肾小球病(ITG)是一种罕见的肾小球疾病形式。其特征是肾小球内有有序的、致密的免疫球蛋白沉积,损害肾小球功能和滤过。预后往往较差,大多数患者会发展为终末期肾病(ESRD)。在此,我们报告一例无前科病史的年轻男性患者,他表现为全身性水肿。其最初表现被认为是因新诊断的射血分数降低的心力衰竭所致。然而,大量蛋白尿导致了ITG的诊断。

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