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一名患有新冠病毒病且前囟膨隆的婴儿:病例报告及文献综述

An Infant With COVID-19 Presenting With a Bulging Fontanel: A Case Report and Literature Review.

作者信息

Kuroda Hiroyuki, Kusama Yoshiki, Ogura Ayu, Matsunaga Takashi, Atsumi Yukari, Kamimura Katsunori

机构信息

Department of Pediatrics, Hyogo Prefectural Amagasaki General Medical Center, Amagasaki, JPN.

Department of Infectious Diseases, Osaka University Hospital, Suita, JPN.

出版信息

Cureus. 2024 Jul 2;16(7):e63667. doi: 10.7759/cureus.63667. eCollection 2024 Jul.

Abstract

A bulging fontanel is a sign of elevated intracranial pressure, which can be caused by diseases with intracranial fluid retention or swelling of the cerebral parenchyma. We experienced a case of an infant with a typical course of mild coronavirus disease 2019 (COVID-19) but with a bulging fontanel as a finding at presentation. The patient, a three-month-old boy with no underlying conditions, presented to the emergency clinic with fever, vomiting, and loss of appetite. Due to the absence of crying and the bulging fontanel, he was referred to our hospital with suspected bacterial meningitis. The diameter of the anterior fontanel was 2.5 cm, as measured by the Popich and Smith method. He showed no signs of consciousness impairment and appeared to be as active as usual. Computed tomography revealed a bulging fontanel. Cerebrospinal fluid examination showed no elevated cell counts, and cultures were negative. Accordingly, bacterial meningitis was ruled out. The fever resolved on the day after admission, and the patient was discharged on the third day after admission in good general condition. When an infant diagnosed with COVID-19 presents with a bulging fontanel, it is important to be aware of its low specificity and excessive antibiotic treatment should be reconsidered.

摘要

囟门膨隆是颅内压升高的体征,可由伴有颅内液体潴留的疾病或脑实质肿胀引起。我们遇到一例婴儿,其患有典型的轻度2019冠状病毒病(COVID-19)病程,但就诊时发现有囟门膨隆。该患者为一名3个月大的男婴,无基础疾病,因发热、呕吐和食欲不振到急诊诊所就诊。由于不哭且囟门膨隆,他因疑似细菌性脑膜炎被转诊至我院。采用波皮奇和史密斯方法测量,前囟直径为2.5厘米。他没有意识障碍的迹象,看起来和平时一样活跃。计算机断层扫描显示囟门膨隆。脑脊液检查显示细胞计数未升高,培养结果为阴性。因此,排除了细菌性脑膜炎。入院后第二天发热消退,患者在入院第三天出院,一般情况良好。当诊断为COVID-19的婴儿出现囟门膨隆时,重要的是要意识到其特异性较低,应重新考虑过度使用抗生素治疗的问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdff/11293365/34c97f1c3e6a/cureus-0016-00000063667-i01.jpg

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