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原发性开角型青光眼行房角分离术和房角切开术的长期疗效。

Long-Term Outcome After Canaloplasty and Phacocanaloplasty in Primary Open Angle Glaucoma.

机构信息

Augentagesklinik Spreebogen.

Berlin Eye Research Institute.

出版信息

J Glaucoma. 2024 Nov 1;33(11):867-873. doi: 10.1097/IJG.0000000000002473. Epub 2024 Aug 5.

DOI:10.1097/IJG.0000000000002473
PMID:39093018
Abstract

PRCIS

Canaloplasty and phacocanaloplasty achieve a statistically significant intraocular pressure (IOP)-reduction for up to 11 years and decrease the long-term need for glaucoma medications. Both procedures have a low long-term complication rate.

PURPOSE

To evaluate the long-term outcome of canaloplasty with and without cataract surgery in primary open angle glaucoma (POAG) patients.

PATIENTS AND METHODS

In all, 48 eyes of 34 patients with POAG who successfully received canaloplasty alone (group A, n=28) or with phacoemulsification (group B, n=20) were retrospectively analyzed. Demographic data, IOP, and IOP-lowering medication were recorded presurgery and postsurgery with a follow-up of up to 14 years.

RESULTS

The mean follow-up time in group A was 91.4±45.0 months. Mean IOP dropped from 22.0±3.8 mm Hg at baseline to 14.0±3.3, 14.3±3.1, 14.4±3.8, and 16.5±1.2 mm Hg at 1, 4, 7, and 10 years, respectively. IOP-lowering medication count decreased from 1.5±1.0 at baseline to 0.1±0.4, 0.3±0.6, 0.6±0.9, and 0.9±1.1 at 1, 4, 7, and 10 years, respectively. The mean follow-up time in group B was 109.1±25.7 months. Mean IOP dropped from 24.5±6.0 at baseline to 13.8±2.9, 14.9±3.6, 15.3±2.9, and 14.8±2.0 mm Hg at 1, 4, 7, and 10 years, respectively. IOP-lowering medication count decreased from 2.2±1.2 before surgery to 0.0, 0.1±0.3, 0.1±0.2, and 0.5±0.9 at 1, 4, 7, and 10 years, respectively.

CONCLUSION

Canaloplasty and phacocanaloplasty achieved a comparable decrease in IOP and glaucoma medication count with a low complication rate. Both procedures showed a high long-term success rate.

摘要

PRCIS

房水引流管成形术和超声乳化白内障吸除术联合房水引流管植入术在长达 11 年内均能显著降低眼内压(IOP),并减少长期青光眼药物治疗的需求。两种手术均具有较低的长期并发症发生率。

目的

评估原发性开角型青光眼(POAG)患者单纯行房水引流管成形术(A 组,n=28)或联合超声乳化白内障吸除术(B 组,n=20)的长期疗效。

患者和方法

回顾性分析 34 例 POAG 患者 48 只眼的资料,所有患者均成功接受了单纯房水引流管成形术(A 组)或联合超声乳化白内障吸除术(B 组)。记录患者的人口统计学数据、IOP 和降眼压药物使用情况,随访时间最长达 14 年。

结果

A 组的平均随访时间为 91.4±45.0 个月。B 组的平均随访时间为 109.1±25.7 个月。与基线相比,A 组的平均 IOP 分别在第 1、4、7 和 10 年时降低至 14.0±3.3、14.3±3.1、14.4±3.8 和 16.5±1.2mmHg,IOP 降低药物计数分别降低至 0.1±0.4、0.3±0.6、0.6±0.9 和 0.9±1.1。B 组的平均 IOP 分别在第 1、4、7 和 10 年时降低至 13.8±2.9、14.9±3.6、15.3±2.9 和 14.8±2.0mmHg,IOP 降低药物计数分别降低至 0.0、0.1±0.3、0.1±0.2 和 0.5±0.9。

结论

房水引流管成形术和超声乳化白内障吸除术联合房水引流管植入术均能降低眼压和青光眼药物使用剂量,具有相似的疗效,且并发症发生率低。两种手术的长期成功率均较高。

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引用本文的文献

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J Clin Med. 2025 Apr 4;14(7):2481. doi: 10.3390/jcm14072481.
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Color Doppler Imaging Assessment of Ocular Blood Flow Following Ab Externo Canaloplasty in Primary Open-Angle Glaucoma.
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