Janin-Mercier A, Mignot P, Delage J, Molina C
Rev Pneumol Clin. 1985;41(4):238-44.
The authors draw attention to the diagnostic value of tissue immunopathology methods in numerous bronchopulmonary diseases. Having emphasized the strict technical requirements and difficulties of these methods--all obstacles that are necessary for an accurate evaluation of the lesion--they use concrete examples to demonstrate the usefulness of extra-thoracic, skin or muscle biopsies to diagnose some systemic diseases, such as lupus erythematosus or Churg and Strauss syndrome. They also refer to bronchial biopsies which provide information on the aetiology and pathogeny of adult asthma, and to the prognostic and therapeutic value of collagen studies in idiopathic pulmonary fibrosis.
作者提请注意组织免疫病理学方法在众多支气管肺部疾病中的诊断价值。在强调了这些方法严格的技术要求和困难——所有这些都是准确评估病变所必需的障碍之后，他们用具体例子展示了胸外、皮肤或肌肉活检在诊断某些全身性疾病（如红斑狼疮或丘-施综合征）方面的有用性。他们还提到了支气管活检可提供有关成人哮喘病因和发病机制的信息，以及胶原研究在特发性肺纤维化中的预后和治疗价值。
