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离体心脏灌流:更新的系统评价。

Ex vivo heart perfusion: an updated systematic review.

机构信息

Cardiac Surgery Unit, Cardio-thoraco-vascular and Public Health Department, Padova University Hospital, Padua, Italy.

Division of Congenital Cardiovascular Surgery, Pediatric Heart Centre and Children's Research Centre, University Children's Hospital Zürich, Zurich, Switzerland.

出版信息

Heart Fail Rev. 2024 Sep;29(5):1079-1096. doi: 10.1007/s10741-024-10420-y. Epub 2024 Aug 2.

DOI:10.1007/s10741-024-10420-y
PMID:39093495
Abstract

Due to the discrepancy between patients awaiting a heart transplant and the availability of donor hearts, strategies to expand the donor pool and improve the transplant's success are crucial. This review aims to summarize current knowledge on the ex vivo heart preservation (EVHP) experience as an alternative to standard cold static storage (CSS). EVHP techniques can improve the preservation of the donor's heart before transplantation and allow for pre-transplant organ evaluation.

摘要

由于等待心脏移植的患者与供体心脏的供应之间存在差异,因此扩大供体池和提高移植成功率的策略至关重要。本综述旨在总结离体心脏保存 (EVHP) 作为标准冷静态保存 (CSS) 的替代方案的现有知识。EVHP 技术可以改善供体心脏在移植前的保存,并允许在移植前对器官进行评估。

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本文引用的文献

1
Nonischemic Donor Heart Preservation: New Milestone in Heart Transplantation History.非缺血性供心保存:心脏移植史上的新里程碑。
ASAIO J. 2023 Aug 1;69(8):725-733. doi: 10.1097/MAT.0000000000002001. Epub 2023 Jun 15.
2
Transplantation Outcomes with Donor Hearts after Circulatory Death.心脏停跳供体捐献者的移植结局。
N Engl J Med. 2023 Jun 8;388(23):2121-2131. doi: 10.1056/NEJMoa2212438.
3
The Role of Daily Implant-Based Multiparametric Telemonitoring in Patients with a Ventricular Assist Device.基于植入物的每日多参数远程监测在心室辅助装置患者中的作用
Life (Basel). 2022 Dec 23;13(1):38. doi: 10.3390/life13010038.
4
Pediatric heart transplantation following donation after circulatory death, distant procurement, and ex-situ perfusion.儿童心脏移植后捐赠后的循环死亡、远距离采购和体外灌注。
J Heart Lung Transplant. 2022 Aug;41(8):1104-1113. doi: 10.1016/j.healun.2022.04.013. Epub 2022 May 4.
5
Long-term outcomes after heart transplantation using ex vivo allograft perfusion in standard risk donors: A single-center experience.应用体外供体器官灌流技术于标准风险供体行心脏移植的长期效果:单中心经验。
Clin Transplant. 2022 May;36(5):e14591. doi: 10.1111/ctr.14591. Epub 2022 Jan 23.
6
Successful heart transplantation after 17 h ex vivo time using the Organ Care System-3 years follow-up.使用 Organ Care System 进行 17 小时体外循环后成功进行心脏移植:3 年随访结果。
J Card Surg. 2021 Jul;36(7):2592-2595. doi: 10.1111/jocs.15519. Epub 2021 Mar 30.
7
Ex Vivo Allograft Perfusion for Complex Pediatric Heart Transplant Recipients.体外同种异体供心灌洗用于复杂儿科心脏移植受者
Ann Thorac Surg. 2021 Oct;112(4):1275-1280. doi: 10.1016/j.athoracsur.2020.12.025. Epub 2021 Jan 7.
8
Heart transplant outcomes in patients with mechanical circulatory support: cold storage versus normothermic perfusion organ preservation.机械循环支持患者心脏移植结局:低温保存与常温灌注器官保存。
Interact Cardiovasc Thorac Surg. 2021 Apr 8;32(3):476-482. doi: 10.1093/icvts/ivaa280.
9
Heart transplantation of patients with ventricular assist devices: impact of normothermic ex-vivo preservation using organ care system compared with cold storage.心脏移植联合心室辅助装置的患者:使用器官保存系统常温保存与低温保存的对比。
J Cardiothorac Surg. 2020 Oct 27;15(1):323. doi: 10.1186/s13019-020-01367-w.
10
DCD donations and outcomes of heart transplantation: the Australian experience.心脏移植的脑死亡后器官捐献(DCD)及结果:澳大利亚的经验
Indian J Thorac Cardiovasc Surg. 2020 Aug;36(Suppl 2):224-232. doi: 10.1007/s12055-020-00998-x. Epub 2020 Aug 15.