Flinders University Institute for Mental Health and Wellbeing and Blackbird Initiative, Flinders University, Adelaide, SA, Australia.
Curr Psychiatry Rep. 2024 Sep;26(9):447-459. doi: 10.1007/s11920-024-01519-y. Epub 2024 Aug 2.
The purpose of this systematic review and meta-analysis was to examine the use and efficacy of acute augmentation therapies in eating disorders.
A meta-analysis addressing this topic across psychological disorders found augmentation significantly improved therapy outcome with strongest findings for augmentations targeting biological mechanisms; however, only one study examined eating disorders. Our systematic review identified 29 studies examining people with eating disorders (N = 1831 participants, 93.7% female), of which 17 RCTs (n = 1162 participants) were included in the meta-analysis. Small subgroups of acute augmentations were identified. Adding acute augmentations to an intervention was effective in 72.4% of studies, with a significant effect on eating disorder outcomes (Hedges' g = 0.14, 95% CI: [0.02, 0.26]). Acute augmentation looks to be a promising approach regardless of weight status or whether it is added to treatment as usual or a single therapy approach.
本系统评价和荟萃分析的目的是研究进食障碍中急性增效治疗的应用和疗效。
一项针对心理障碍的荟萃分析发现,增效治疗显著改善了治疗效果,针对生物学机制的增效治疗效果最强;然而,只有一项研究检查了进食障碍。我们的系统评价确定了 29 项研究,涉及患有进食障碍的人(N=1831 名参与者,93.7%为女性),其中 17 项 RCT(n=1162 名参与者)被纳入荟萃分析。确定了急性增效治疗的小亚组。将急性增效治疗添加到干预措施中,在 72.4%的研究中是有效的,对进食障碍结果有显著影响(Hedges'g=0.14,95%CI:[0.02, 0.26])。无论体重状况如何,或是否添加到常规治疗或单一治疗方法中,急性增效治疗似乎都是一种很有前途的方法。