Division of Neonatology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Division of Nutritional Sciences, University of Cincinnati, Cincinnati, Ohio, USA.
Breastfeed Med. 2024 Oct;19(10):779-787. doi: 10.1089/bfm.2024.0052. Epub 2024 Aug 2.
Rates of mother's own milk (MOM) provision in the neonatal intensive care unit (NICU) vary widely, despite acceptance as the gold standard for nutrition in preterm infants. Direct breastfeeding (DBF) supports long-term provision of MOM, but factors that support DBF in preterm infants are unknown. The purpose of this study was to identify factors that predict DBF at oral feeding initiation and at NICU discharge. This was a retrospective cohort study of preterm infants born at ≤ 32 weeks who were receiving MOM at 32 weeks corrected gestational age (cohort 1) and at discharge to home (cohort 2). The primary outcomes were rates of DBF at oral feeding initiation (cohort 1) and at hospital discharge (cohort 2). We examined bivariate associations between infant characteristics, maternal sociodemographic factors, and hospital practices (e.g., lactation visit timing and frequency) with DBF outcomes and then built logistic regression models to determine the adjusted odds ratio and 95% confidence interval ([adjusted odds ratio [aOR] [95%CI]) for independent predictors of the DBF outcomes. Sixty-four percent of eligible infants initiated DBF, and 51% were DBF at discharge. Sociodemographic, NICU, and lactation support factors were associated with both outcomes. Post hoc analysis showed that similar factors also influenced lactation support provision. Lactation support, NICU and sociodemographic variables influence DBF initiation and DBF at discharge. Interventions that optimize efficient use of available lactation support, address bias, and provide ample opportunity for DBF practice could improve rates.
尽管母乳喂养被认为是早产儿营养的金标准,但新生儿重症监护病房(NICU)中母亲提供母乳(MOM)的比例差异很大。直接母乳喂养(DBF)支持长期提供 MOM,但支持早产儿 DBF 的因素尚不清楚。本研究的目的是确定预测 DBF 在口腔喂养开始和 NICU 出院时的因素。
这是一项回顾性队列研究,纳入了在 32 周时接受 MOM 的≤32 周出生的早产儿,研究分为两组:在 32 周校正胎龄时开始口腔喂养的早产儿(队列 1)和出院回家的早产儿(队列 2)。主要结局是口腔喂养开始(队列 1)和出院(队列 2)时的 DBF 率。我们检查了婴儿特征、产妇社会人口统计学因素和医院实践(例如,母乳喂养就诊时间和频率)与 DBF 结局之间的单变量关联,然后建立了逻辑回归模型,以确定 DBF 结局的独立预测因素的调整后优势比和 95%置信区间([调整后优势比 [aOR] [95%CI])。符合条件的婴儿中有 64%开始 DBF,51%在出院时进行 DBF。社会人口统计学、NICU 和哺乳支持因素与这两个结局都有关。事后分析表明,类似的因素也影响了哺乳支持的提供。
哺乳支持、NICU 和社会人口统计学变量影响 DBF 开始和出院时的 DBF。优化现有哺乳支持的有效利用、解决偏见和提供充足的 DBF 实践机会的干预措施可以提高比率。