Translational and Clinical Research Institute, Newcastle University Centre for Cancer, Newcastle upon Tyne, UK; Northern Centre for Cancer Care, Freeman Hospital, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Translational and Clinical Research Institute, Newcastle University Centre for Cancer, Newcastle upon Tyne, UK; Northern Centre for Cancer Care, Freeman Hospital, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Eur Urol Focus. 2024 May;10(3):361-363. doi: 10.1016/j.euf.2024.06.011. Epub 2024 Aug 1.
Treatment de-escalation strategies in patients with seminoma with retroperitoneal metastases are being investigated in ongoing clinical trials. Primary retroperitoneal lymph node dissection conducted by expert surgeons may avoid any cytotoxic treatment and related long-term side effects in ≥70% of patients with clinical stage IIA/B seminoma.
目前正在进行的临床试验正在研究腹膜后转移的精原细胞瘤患者的降阶梯治疗策略。由专家外科医生进行的原发性腹膜后淋巴结清扫术可能使≥70%的临床 IIA/B 期精原细胞瘤患者避免任何细胞毒性治疗及其相关的长期副作用。
