人类白细胞抗原配型与尸体肾移植——1984年的现状
HLA matching and cadaver kidney transplantation--status 1984.
作者信息
Opelz G
出版信息
Ulster Med J. 1985 Aug;54 Suppl(Suppl):S70-5.
The effect of HLA matching on cadaver kidney graft survival was analysed in over 9000 transplants. Matching for HLA-A and -B accounted for an improvement of 8% in the one-year survival rate, matching for HLA-DR for 10%, and matching for HLA-B + DR for 19%. The matching effect of the HLA-B and HLA-DR loci was additive. Patients without pre-transplant transfusions had lower graft survival rates than transfused patients, even if their grafts were HLA matched. The highest success rate was obtained in transfused recipients who received HLA matched kidneys.
对9000多例移植手术分析了HLA配型对尸体肾移植存活的影响。HLA - A和 - B配型使一年存活率提高了8%，HLA - DR配型提高了10%，HLA - B + DR配型提高了19%。HLA - B和HLA - DR位点的配型效果是累加的。未进行移植前输血的患者，即使其移植肾HLA配型，其移植肾存活率也低于输血患者。接受HLA配型肾移植的输血受者成功率最高。
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