Wahlberg J, Backman U, Frödin L, Stenkvist B, Tufveson G
Ups J Med Sci. 1985;90(2):163-8. doi: 10.3109/03009738509178654.
Fine-needle aspiration biopsy( FNAB) of renal allograft transplants has been used at Uppsala University Hospital for 3 years. Experience from 51 consecutive patients (from 1 1/2 years) with 333 FNAB was reviewed. Representative material was obtained in more than 70% of the biopsies. Eleven rejection episodes in 12 patients were confirmed with this method. One was not recognized. Significant inflammation in the kidney without clinical rejection was found in 22 patients. The possible causes of such inflammation are discussed. Repeatedly recorded inflammation in the kidney with minor or no effect on graft function may sometimes be caused by viral infection. The clinical value of FNAB in various immunosuppressive regimens is discussed.
细针穿刺活检（FNAB）已在乌普萨拉大学医院用于肾移植患者3年。回顾了51例连续患者（1年半时间内）接受333次细针穿刺活检的经验。超过70%的活检获取到了代表性样本。通过该方法确诊了12例患者中的11次排斥反应。1次未被识别。22例患者在无临床排斥反应的情况下发现肾脏存在显著炎症。讨论了这种炎症的可能原因。肾脏反复出现炎症但对移植肾功能影响较小或无影响，有时可能是由病毒感染引起的。讨论了细针穿刺活检在各种免疫抑制方案中的临床价值。
