School of Medicine, Università Campus Bio-Medico di Roma, Rome, Italy.
Unit of Integrated Therapies in Otolaryngology, Fondazione Policlinico Universitario Campus Bio- Medico, Rome, Italy.
Sleep Breath. 2024 Oct;28(5):2107-2115. doi: 10.1007/s11325-024-03127-9. Epub 2024 Aug 3.
Among the treatment options for Obstructive Sleep Apnea (OSA), intrapharyngeal surgery has undergone significant changes and received solid scientific support. However, it is crucial to identify the best candidate. This study aims to present the results of the modified Alianza technique in our clinic to show the differences in the impact of surgery on supine and non-supine apnea levels in moderate-severe OSA patients.
Adult patients affected by moderate-severe OSA (Apnea-Hypopnea Index (AHI) > 15), having circular palatal collapse, and candidates for modified Alianza Tecnique were retrospectively enrolled. Each subject performed polysomnography pre- and post-operatively, and the follow-up check was performed after at least six months.
This study enrolled 24 patients who underwent the Modified Alianza technique for sleep apnea. We found significant reductions in both supine and non-supine AH) after surgery. Non-supine AHI showed a greater reduction (from 20.89 to 11.64 episodes/hour, p = 0.0001) than supine AHI (from 42.51 to 25.93, p = 0.0003). We subsequently divided the patients into two groups based on whether they were affected by positional OSA before surgery. There was a lower percentage decrease in non-supine AHI compared to supine AHI after surgery in patients who were positional before surgery, but this difference was not statistically significant. Conversely, in the non-positional patient group, there was a higher decrease in non-supine AHI compared to supine AHI, although this was not statistically significant.
The Modified Alianza Tecnique leads to notable enhancement in AHI among patients with OSA. Non-supine apneas exhibit a more favorable response to the surgery than supine apneas.
在阻塞性睡眠呼吸暂停(OSA)的治疗选择中,咽内手术经历了重大变化,并得到了坚实的科学支持。然而,确定最佳候选者至关重要。本研究旨在展示我们诊所中改良 Alianza 技术的结果,以展示手术对中重度 OSA 患者仰卧位和非仰卧位呼吸暂停水平影响的差异。
回顾性纳入受中重度 OSA(呼吸暂停低通气指数(AHI)> 15)影响、存在环状软腭裂塌陷且为改良 Alianza 技术候选者的成年患者。每位患者在术前和术后均进行多导睡眠图检查,并且在至少 6 个月后进行随访检查。
本研究共纳入 24 例接受改良 Alianza 技术治疗睡眠呼吸暂停的患者。我们发现术后仰卧位和非仰卧位 AHI 均显著降低。非仰卧位 AHI 的降低幅度(从 20.89 降至 11.64 次/小时,p=0.0001)大于仰卧位 AHI 的降低幅度(从 42.51 降至 25.93,p=0.0003)。随后,我们根据患者术前是否存在位置性 OSA 将其分为两组。术前存在位置性 OSA 的患者,术后非仰卧位 AHI 的百分比降低幅度低于仰卧位 AHI,但差异无统计学意义。相反,在非位置性患者组中,非仰卧位 AHI 的降低幅度高于仰卧位 AHI,但差异无统计学意义。
改良 Alianza 技术可显著改善 OSA 患者的 AHI。非仰卧位呼吸暂停对手术的反应优于仰卧位呼吸暂停。