Key Laboratory of Interfacial Reaction & Sensing Analysis in Universities of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, PR China.
Shandong Institute for Food and Drug Control, Key Laboratory of Supervising Technology for Meat and Meat Products for State Market Regulation, Shandong Research Center of Engineering and Technology for Quality Control of Food for Special Medical Purposes, Shandong Research Center of Engineering and Technology for Safety Inspection of Food and Drug, Jinan 250101, PR China.
J Chromatogr A. 2024 Sep 13;1732:465200. doi: 10.1016/j.chroma.2024.465200. Epub 2024 Jul 20.
A covalent organic framework (COF) was gown on porous silica with 1,3,5-tri(4-aminophenyl)benzene and 2,5-divinyl-1,4-phenyldiformaldehyde as monomers, and two ionic liquids were grafted to COF by a click reaction. The materials before and after the modification of ionic liquids were separately packed into solid-phase extraction columns (10 × 4.6 mm, i.d.), which were coupled with liquid chromatography to construct online analysis systems. The extraction mechanisms of polycyclic aromatic hydrocarbons, bisphenols, diphenylalkanes and benzoic acids were investigated on these materials. There were π-π, hydrogen-bond and electrostatic interactions on ionic liquid-functionalized sorbents. After the comparison among these materials, the best sorbent was used, and the analytical method was established and successfully applied to the detection of some estrogens from actual samples. For the analytical method, the detection limit was as low as 0.005 μg L, linear range was as wide as 0.017-10.0 μg L, and enrichment ratio was as high as 3635. The recoveries in actual samples were 70 %-129 %.
一种共价有机骨架（COF）在多孔硅上生长，使用的单体为 1,3,5-三（4-氨基苯基）苯和 2,5-二乙烯基-1,4-苯二甲醛，两种离子液体通过点击反应接枝到 COF 上。离子液体修饰前后的材料分别填充到固相萃取柱（10×4.6mm，内径）中，与液相色谱法耦合，构建在线分析系统。在这些材料上研究了多环芳烃、双酚、二芳基烷烃和苯甲酸的萃取机理。离子液体功能化的吸附剂上存在π-π、氢键和静电相互作用。在比较这些材料之后，选择了最佳的吸附剂，建立了分析方法，并成功地应用于实际样品中一些雌激素的检测。对于分析方法，检测限低至 0.005μg/L，线性范围宽至 0.017-10.0μg/L，富集比高达 3635。实际样品中的回收率为 70%-129%。
