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M.A.R.试验在快速检测不育男性抗精子自身免疫方面的作用。

The M.A.R. test role for a rapid detection of antisperm autoimmunization in infertile men.

作者信息

Cimino C, Barba G

出版信息

Acta Eur Fertil. 1985 Sep-Oct;16(5):347-53.

PMID:3909708
Abstract

We examined 44 men from couples with negative or dubious P.C.T. which had not been caused by cervical pathology (infection, malformative pathology or insufficient mucus production) or seminal pathology (no infection present, normal seminal liquid and in some cases at the most a slight asthenospermia). 40,9% of the men were classified as immunized. This was established by the results of seric T.A.T. and other tests. The M.A.R. test has proved to be a good method for the screening of immunization in those with a low sperm-motility; in fact results proved either positive or strongly positive in 83,3% of immunized subjects. Considering as positive the M.A.R. tests which were "doubtfully positive", the final results proved positive in 94,4% of immunized subjects.

摘要

我们检查了44名男性,他们来自夫妇双方抗精子抗体检测呈阴性或可疑的情况,且并非由宫颈病理状况(感染、畸形病理或黏液分泌不足)或精液病理状况(无感染、精液正常,某些情况下最多有轻微弱精子症)引起。40.9%的男性被归类为免疫状态。这是根据血清破伤风抗毒素(T.A.T.)及其他检测结果确定的。抗精子抗体相关反应(M.A.R.)试验已被证明是筛查精子活力低者免疫状态的一种好方法;事实上,在83.3%的免疫受试者中,该试验结果呈阳性或强阳性。将“可疑阳性”的M.A.R.试验视为阳性,最终结果显示94.4%的免疫受试者呈阳性。

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