Grupo NanoBioCel, Laboratorio de farmacéuticos, Escuela de Farmacia, Universidad del País Vasco UPV/EHU, Vitoria-Gasteiz, España.
Servicio de Farmacia, Servicio de Salud de Osakidetza, Organización Sanitaria Integrada de Debagoiena, Gipuzkoa, España; Bioaraba, Clinical Pharmacy Research Group, Vitoria-Gasteiz, España.
Farm Hosp. 2024 Jul;48 Suppl 1:S13-S20. doi: 10.1016/j.farma.2023.09.010.
Drugs do not disappear once they have been excreted. In fact, 992 active principles have already been measured in the different environmental matrices. A recent study led by scientists from the University of York has studied the presence of drugs in the rivers of more than 100 different countries, showing that environmental contamination by pharmaceuticals is a global issue and that, concentrations found are frequently harmful to the environment. In this work, we have tried to briefly expose the problem of environmental contamination with medicines, but above all, we have tried to address the possible solutions, with a perspective from the field of hospital pharmacy. This is a very complex matter (a wicked problem), since it involves multiple stakeholders with different visions and interests regarding medicines. In order to find solutions, we will probably need to act at all steps of the drug's life cycle. Until now, health professionals have been part of the problem. It is time for us to be part of the solution.
药物一旦被排泄就不会消失。事实上,已经在不同的环境基质中测量到 992 种活性物质。最近一项由约克大学科学家领导的研究调查了 100 多个不同国家河流中药物的存在情况,结果表明,药物对环境的污染是一个全球性问题,而且发现的浓度经常对环境有害。在这项工作中,我们试图简要地揭示药物对环境造成的污染问题,但最重要的是,我们试图从医院药剂科的角度来探讨可能的解决方案。这是一个非常复杂的问题(一个棘手的问题),因为它涉及到多个利益相关者,他们对药物有不同的看法和利益。为了找到解决方案,我们可能需要在药物生命周期的各个阶段采取行动。到目前为止,卫生专业人员一直是问题的一部分。现在是我们成为解决方案的一部分的时候了。