Tallroth K, Vankka E
Acta Radiol Diagn (Stockh). 1985 Nov-Dec;26(6):757-60. doi: 10.1177/028418518502600622.
The first clinical experience with the new contrast medium, iohexol, in shoulder arthrography is reported. A double-blind comparison of iohexol and meglumine iothalamate, a conventional medium in standard use for arthrography, was carried out in a consecutive series of 60 adult patients forming two groups of 30 subjects each. No difference in the radiographic quality was seen immediately after contrast injection but in exposures at 20 min iohexol gave a significantly better arthrographic quality. Practically no adverse effects occurred during the examinations. Although minor side effects were numerous in both groups during the two days following arthrography, they were somewhat more frequent in patients given iothalamate.
本文报道了新型造影剂碘海醇在肩关节造影中的首次临床应用经验。对60例成年患者进行了连续研究，将其分为两组，每组30人，对碘海醇和传统造影剂甲泛葡胺进行双盲对比研究。造影剂注射后立即观察，两组的放射影像质量无差异，但在注射后20分钟进行X线曝光时，碘海醇组的造影质量明显更好。检查过程中几乎未出现不良反应。虽然在造影后的两天内两组患者均出现了较多轻微副作用，但甲泛葡胺组的副作用更为常见。
