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成人患者神经内分泌肿瘤导致的回肠-回肠型肠套叠。

Ileo-Ileal Intussusception Secondary to Neuroendocrine Tumor in Adult Patient.

机构信息

Department of Internal Medicine, Brookwood Baptist Health, Birmingham, AL, USA.

出版信息

Am J Case Rep. 2024 Aug 4;25:e944872. doi: 10.12659/AJCR.944872.

DOI:10.12659/AJCR.944872
PMID:39097769
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11318702/
Abstract

BACKGROUND Intussusception occurs when a proximal region of the intestine telescopes into a distal region. It is more common in the pediatric population, with only 5% of cases occurring in adults. The most frequent causes of adult intussusception are malignancy, polyps, or diverticula. A very rare cause is neuroendocrine tumor (NET). NETs are a diverse group of neoplasms that arise from endocrine cells throughout the body. Here, we present a case of a patient who presented with ileo-ileal intussusception due to a T3N1 NET, grade 1. CASE REPORT A 60-year-old man with a medical history of peptic ulcer disease presented for evaluation of lower abdominal pain, dark "maroon" colored stools, and hematemesis for the past 2 days. Computed tomography (CT) of the abdomen and pelvis showed ileo-ileal intussusception. Exploratory laparotomy revealed a small bowel mass approximately 30 cm from the ileocecal valve. After removal of 15 cm of small bowel and 13 lymph nodes, pathology confirmed the diagnosis of a T3N1 NET, grade 1. He was subsequently referred to the Oncology Department, where he was cleared, with no need for additional surveillance. CONCLUSIONS In adult patients presenting with nonspecific abdominal pain and concern for small bowel obstruction, a CT scan can be helpful in diagnosing intussusception. When dealing with adult intussusception, the etiology needs to be carefully investigated to search for an underlying malignancy. In rare occasions, small bowel NETs can be the cause of intussusception and can therefore be identified early, before they metastasize and present with carcinoid syndrome.

摘要

背景

肠套叠是指一段肠管套入其相连的肠腔内。这种疾病在儿科人群中更为常见,只有 5%的病例发生在成年人中。成人肠套叠最常见的原因是恶性肿瘤、息肉或憩室。非常罕见的原因是神经内分泌肿瘤(NET)。NET 是一组起源于全身内分泌细胞的异质性肿瘤。在这里,我们报告了一例因 T3N1 NET、1 级引起的回-回肠套叠的患者。

病例报告

一名 60 岁男性,有消化性溃疡病史,因下腹疼痛、“暗栗色”大便和过去 2 天呕血就诊。腹部和骨盆 CT 显示回-回肠套叠。剖腹探查显示回盲瓣附近约 30cm 的小肠肿块。切除 15cm 小肠和 13 个淋巴结后,病理证实诊断为 T3N1 NET、1 级。随后他被转至肿瘤科,经评估后无需进一步监测。

结论

对于出现非特异性腹痛且疑似小肠梗阻的成年患者,CT 扫描有助于诊断肠套叠。在处理成人肠套叠时,需要仔细调查病因,以寻找潜在的恶性肿瘤。在极少数情况下,小肠 NET 可能是肠套叠的原因,并因此可以在转移并出现类癌综合征之前早期识别。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd4c/11318702/3a1ee2b71ac6/amjcaserep-25-e944872-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd4c/11318702/7bcf72c4505e/amjcaserep-25-e944872-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd4c/11318702/0413df6c92f6/amjcaserep-25-e944872-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd4c/11318702/1dc743560f2c/amjcaserep-25-e944872-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd4c/11318702/56a892be0f1c/amjcaserep-25-e944872-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd4c/11318702/3a1ee2b71ac6/amjcaserep-25-e944872-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd4c/11318702/7bcf72c4505e/amjcaserep-25-e944872-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd4c/11318702/0413df6c92f6/amjcaserep-25-e944872-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd4c/11318702/1dc743560f2c/amjcaserep-25-e944872-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd4c/11318702/56a892be0f1c/amjcaserep-25-e944872-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd4c/11318702/3a1ee2b71ac6/amjcaserep-25-e944872-g005.jpg

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本文引用的文献

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Gastroduodenal intussusception. An insidious complication following gastric plication.胃十二指肠套叠。胃折叠术后的一种隐匿性并发症。
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