Department of Rehabilitation Medicine, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou 215008, Jiangsu, China.
Department of Rehabilitation Medicine, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou 215008, Jiangsu, China.
Psychiatry Res Neuroimaging. 2024 Sep;343:111866. doi: 10.1016/j.pscychresns.2024.111866. Epub 2024 Aug 2.
The involvement of the right hemisphere, mainly the activation of the right cerebral regions, in recovery from post-stroke aphasia has been widely recognized. In contrast, the role of the right white matter pathways in the recovery from post-stroke aphasia is rarely understood. In this study, we aimed to provide a primary overview of the correlation between the structural integrity of the right hemispheric neural tracts based on the dual-stream model of language organization and recovery from post-stroke aphasia by systematically reviewing prior longitudinal interventional studies. By searching electronic databases for relevant studies according to a standard protocol, a total of 10 records (seven group studies and three case studies) including 79 participants were finally included. After comprehensively analyzing these studies and reviewing the literature, although no definite correlation was found between the right hemispheric neural tracts and recovery from post-stroke aphasia, our review provideds a new perspective for investigating the linguistic role of the right hemispheric neural tracts. This suggests that the involvement of the right hemispheric neural tracts in recovery from post-stroke aphasia may be mediated by multiple factors; thus, this topic should be comprehensively investigated in the future.
右侧大脑半球（主要是右大脑区域的激活）在中风后失语症的恢复中起着重要作用，这一观点已得到广泛认可。相比之下，右侧白质通路在中风后失语症恢复中的作用却鲜为人知。在本研究中，我们旨在通过系统综述先前的纵向干预研究，初步概述基于语言组织双通道模型的右侧半球神经束结构完整性与中风后失语症恢复之间的相关性。根据标准方案，通过搜索电子数据库，最终纳入了 10 项研究（7 项群组研究和 3 项病例研究），共包括 79 名参与者。在全面分析这些研究并回顾文献后，尽管我们没有发现右侧半球神经束与中风后失语症恢复之间存在明确的相关性，但我们的综述为研究右侧半球神经束的语言作用提供了新的视角。这表明右侧半球神经束在中风后失语症恢复中的作用可能受到多种因素的影响，因此，这个话题应该在未来得到全面的研究。
