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农村地区新冠肺炎合并肺炎的死亡率

Mortality Rate of COVID-19 With Comorbid Pneumonia in a Rural Area.

作者信息

Multani Anmol, Kollipara Vineesha, Krage Tess, Hearn James, Stahl Greg, Johnson Kerry, Goade Scott, Beyersdorfer Nova, Arnce Robert D

机构信息

College of Osteopathic Medicine, Kansas City University, Joplin, USA.

Clinical Research, Freeman Health System, Joplin, USA.

出版信息

Cureus. 2024 Jul 3;16(7):e63780. doi: 10.7759/cureus.63780. eCollection 2024 Jul.

Abstract

BACKGROUND

A myriad of risk factors and comorbidities have been determined to influence COVID-19 mortality rates; among these is pneumonia. This study considers pneumonia as a risk factor for increased mortality in patients admitted with COVID-19 in a rural healthcare system. We predicted that the presence of pneumonia of any kind would increase mortality rates in patients admitted with COVID-19.

METHODS

A retrospective observational study was conducted using data collected from hospitals in the Freeman Health System (FHS) located in Joplin and Neosho, Missouri. Data were collected between April 1, 2020, and December 31, 2021. Using International Classification of Diseases, Tenth Revision (ICD-10) codes, the investigators identified five distinct patient populations: patients with COVID-19 and pneumonia due to COVID-19 (P1); patients with COVID-19 but without pneumonia due to COVID-19 (P2); patients with COVID-19 and any type of pneumonia (P3); patients with COVID-19 but without any type of pneumonia (P4); and patients without COVID-19 and with any type of pneumonia (P5). In order to understand how pneumonia influences COVID-19 outcomes, the investigators used Wald's method and a two-sample proportion summary hypothesis test to determine the confidence interval and to compare the mortality rates between these populations, respectively.

RESULTS

The population of patients with COVID-19 and any type of pneumonia (P3) and the population of patients with COVID-19 and pneumonia due to COVID-19 (P1) showed the highest mortality rates. The population of patients with COVID-19 but without any type of pneumonia (P4) had the lowest mortality rate. The data revealed that having pneumonia combined with COVID-19 in any patient population led to a higher mortality rate than COVID-19 alone.

CONCLUSION

Mortality rates were higher among COVID-19 patients with pneumonia compared to COVID-19 patients without pneumonia. Additionally, pneumonia, by itself, was found to have a higher mortality rate compared to COVID-19 alone.

摘要

背景

已确定众多风险因素和合并症会影响新冠病毒疾病(COVID-19)的死亡率;其中包括肺炎。本研究将肺炎视为农村医疗系统中因COVID-19入院患者死亡率增加的一个风险因素。我们预测,任何类型的肺炎都会增加因COVID-19入院患者的死亡率。

方法

采用回顾性观察研究,使用从位于密苏里州乔普林和尼奥肖的弗里曼医疗系统(FHS)的医院收集的数据。数据收集时间为2020年4月1日至2021年12月31日。研究人员使用国际疾病分类第十版(ICD-10)编码,确定了五个不同的患者群体:因COVID-19患有COVID-19和肺炎的患者(P1);因COVID-19患有COVID-19但无肺炎的患者(P2);因COVID-19患有COVID-19和任何类型肺炎的患者(P3);因COVID-19患有COVID-19但无任何类型肺炎的患者(P4);以及无COVID-19但患有任何类型肺炎的患者(P5)。为了了解肺炎如何影响COVID-19的预后,研究人员分别使用沃尔德方法和双样本比例汇总假设检验来确定置信区间并比较这些群体之间的死亡率。

结果

因COVID-19患有任何类型肺炎的患者群体(P3)和因COVID-19患有COVID-19和肺炎的患者群体(P1)的死亡率最高。因COVID-19患有COVID-19但无任何类型肺炎的患者群体(P4)的死亡率最低。数据显示,在任何患者群体中,患有肺炎合并COVID-19的患者死亡率高于仅患有COVID-19的患者。

结论

与无肺炎的COVID-19患者相比,患有肺炎的COVID-19患者死亡率更高。此外,发现肺炎本身的死亡率高于仅患有COVID-19的患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73e3/11297188/2dccd048d64c/cureus-0016-00000063780-i01.jpg

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