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恶性肿瘤患者中抑郁症的患病率是否因诊断方法而异:一项比较四种诊断方法的研究。

Does the prevalence of depression in patients with malignancies vary with the diagnostic approach: A study comparing the four diagnostic approaches.

作者信息

Mishra Eepsita, Nanjaiya Subodh Bhagyalaxmi, Ghoshal Sushmita, Grover Sandeeep

机构信息

Department of Psychiatry, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Department of Radiotherapy, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

Indian J Psychiatry. 2024 Jun;66(6):566-571. doi: 10.4103/indianjpsychiatry.indianjpsychiatry_149_24. Epub 2024 Jun 19.

Abstract

BACKGROUND

Very few studies have compared different diagnostic approaches to diagnose depression in patients with cancers.

AIM

To compare the different diagnostic approaches used for diagnosing depression in patients with cancers.

METHODOLOGY

This cross-sectional study included 200 patients (diagnosed with cancer at least 3 months prior to recruitment) attending the outpatient services who were assessed on diagnostic and statistical manual, fifth edition (DSM-5) criteria for depression. Additionally, these patients were also assessed using the inclusive, exclusive, and substitutive criteria for depression using a semistructured interview. Patients completed Patient Health Questionnaire-9 (PHQ-9).

RESULTS

The mean age of the patients was 50.28 years (S.D. M14.11). Females outnumbered males. The mean age of onset of malignancy was 47 years (S.D 14.03), and the mean time since diagnosis of cancer was 35.45 years (S.D 36.87). The prevalence of depression was the highest (38.5%) when estimated using the PHQ-9 and was the lowest (21.5%) when assessed using exclusive criteria for depression. All approaches had high degree of concordance with the DSM-5 criteria for depression.

CONCLUSION

A significant proportion of patients with cancer suffer from depression, and the prevalence is influenced by the diagnostic method.

摘要

背景

很少有研究比较诊断癌症患者抑郁症的不同方法。

目的

比较用于诊断癌症患者抑郁症的不同诊断方法。

方法

这项横断面研究纳入了200名门诊患者(在招募前至少3个月被诊断为癌症),根据《精神疾病诊断与统计手册》第五版(DSM-5)的抑郁症标准进行评估。此外,还使用半结构化访谈,根据抑郁症的包容性、排他性和替代性标准对这些患者进行评估。患者完成了患者健康问卷-9(PHQ-9)。

结果

患者的平均年龄为50.28岁(标准差14.11)。女性人数多于男性。恶性肿瘤的平均发病年龄为47岁(标准差14.03),自诊断癌症以来的平均时间为35.45年(标准差36.87)。使用PHQ-9评估时抑郁症患病率最高(38.5%),使用抑郁症排他性标准评估时患病率最低(21.5%)。所有方法与DSM-5抑郁症标准的一致性程度都很高。

结论

相当一部分癌症患者患有抑郁症,患病率受诊断方法影响。

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本文引用的文献

1
Performance of four diagnostic approaches to depression in adults with cancer.成人癌症患者中四种抑郁诊断方法的表现。
Gen Hosp Psychiatry. 2018 Mar-Apr;51:90-95. doi: 10.1016/j.genhosppsych.2018.01.006. Epub 2018 Jan 31.
7
Assessment of depression in cancer patients.癌症患者抑郁状况的评估。
J Natl Cancer Inst Monogr. 2004(32):80-92. doi: 10.1093/jncimonographs/lgh013.
9
Depression in cancer patients.癌症患者的抑郁症
Lancet Oncol. 2001 Aug;2(8):499-505. doi: 10.1016/S1470-2045(01)00456-9.

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