Inoue Soki, Tachibana Koichi, Masunaga Nobutaka, Shinoda Yukinori, Minamisaka Tomoko, Inui Hirooki, Ueno Keisuke, Amiya Ryohei, Murakami Arisa, Hoshida Shiro
Department of Cardiovascular Medicine, Yao Municipal Hospital, Yao, Osaka, Japan.
J Cardiol Cases. 2024 Feb 15;29(5):231-233. doi: 10.1016/j.jccase.2024.01.008. eCollection 2024 May.
Acute purulent pericarditis is a rare infection in developed countries. We herein report a case with diabetic nephropathy under maintenance hemodialysis who suffered from acute purulent pericarditis caused by methicillin-resistant (MRSA). The treatment of purulent pericarditis mainly involves rapid administration of appropriate antibiotics and drainage. However, in this case, the patient was unresponsive to vancomycin and performing early surgical intervention was challenging due to highly pathogenic MRSA. Therefore, we performed pericardial fenestration in the chronic phase to suppress the risk of fatal secondary infections after daily irrigation for one month to reduce bacterial load mechanically.
In a case of purulent pericarditis caused by highly pathogenic methicillin-resistant resistant to antibiotics and resulting in constrictive pericarditis, it was possible to perform pericardial fenestration in the chronic phase, while mitigating the risk of fatal secondary infections, by controlling the inflammation through daily irrigation for a long time to reduce the bacterial load mechanically.
在发达国家,急性化脓性心包炎是一种罕见的感染性疾病。我们在此报告一例维持性血液透析的糖尿病肾病患者,该患者患有由耐甲氧西林金黄色葡萄球菌(MRSA)引起的急性化脓性心包炎。化脓性心包炎的治疗主要包括迅速给予适当的抗生素和引流。然而,在该病例中,患者对万古霉素无反应,且由于高致病性MRSA,早期进行手术干预具有挑战性。因此,我们在慢性期进行了心包开窗术,在每日冲洗一个月以机械性降低细菌负荷后,抑制致命性继发感染的风险。
在一例由高致病性耐甲氧西林金黄色葡萄球菌引起的、对抗生素耐药并导致缩窄性心包炎的化脓性心包炎病例中,通过长时间每日冲洗以机械性降低细菌负荷来控制炎症,从而在慢性期进行心包开窗术,同时降低致命性继发感染的风险是可行的。