Sylvester Beau, Fuller Spencer D, Certain Laura, Shakoor Akbar, Doan Thuy
Department of Ophthalmology and Visual Sciences, Washington University School of Medicine in St. Louis, St. Louis, USA.
Department of Ophthalmology and Visual Sciences, University of Utah School of Medicine, Salt Lake City, USA.
Am J Ophthalmol Case Rep. 2024 Jul 4;36:102097. doi: 10.1016/j.ajoc.2024.102097. eCollection 2024 Dec.
We describe a case of severe scleritis possibly caused by .
Conventional laboratory evaluation was inconclusive. The associated organism was identified with metagenomic RNA deep sequencing (MDS). The infection resolved with trimethoprim-sulfamethoxazole treatment.
This case demonstrates the utility of unbiased, high-throughput sequencing for infectious scleritis.
我们描述了一例可能由……引起的严重巩膜炎病例。
传统实验室评估结果不明确。通过宏基因组RNA深度测序(MDS)鉴定出相关病原体。经甲氧苄啶-磺胺甲恶唑治疗后感染得到缓解。
该病例证明了无偏倚的高通量测序在感染性巩膜炎中的应用价值。