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相关的严重坏死性巩膜感染

associated severe necrotizing scleral infection.

作者信息

Sylvester Beau, Fuller Spencer D, Certain Laura, Shakoor Akbar, Doan Thuy

机构信息

Department of Ophthalmology and Visual Sciences, Washington University School of Medicine in St. Louis, St. Louis, USA.

Department of Ophthalmology and Visual Sciences, University of Utah School of Medicine, Salt Lake City, USA.

出版信息

Am J Ophthalmol Case Rep. 2024 Jul 4;36:102097. doi: 10.1016/j.ajoc.2024.102097. eCollection 2024 Dec.

Abstract

PURPOSE

We describe a case of severe scleritis possibly caused by .

OBSERVATIONS

Conventional laboratory evaluation was inconclusive. The associated organism was identified with metagenomic RNA deep sequencing (MDS). The infection resolved with trimethoprim-sulfamethoxazole treatment.

CONCLUSIONS

This case demonstrates the utility of unbiased, high-throughput sequencing for infectious scleritis.

摘要

目的

我们描述了一例可能由……引起的严重巩膜炎病例。

观察结果

传统实验室评估结果不明确。通过宏基因组RNA深度测序(MDS)鉴定出相关病原体。经甲氧苄啶-磺胺甲恶唑治疗后感染得到缓解。

结论

该病例证明了无偏倚的高通量测序在感染性巩膜炎中的应用价值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0628/11294693/975db1655950/gr1.jpg

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