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自发性十二指肠皮肤瘘:十二指肠溃疡穿孔的一种罕见表现。

Spontaneous duodenocutaneous fistula: a rare presentation of perforated duodenal ulcer.

作者信息

Barreto Isabel, Kohler Arnold, Fahrner René

机构信息

Department of Surgery, Bürgerspital Solothurn, CH-4500 Solothurn, Switzerland.

Department of Surgery, University Hospital Zürich, University of Zürich, Zürich, Switzerland.

出版信息

Innov Surg Sci. 2024 Apr 9;9(2):109-112. doi: 10.1515/iss-2023-0051. eCollection 2024 Jun.

DOI:10.1515/iss-2023-0051
PMID:39100721
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11294516/
Abstract

OBJECTIVES

Fistula formation between the duodenum and the skin of the anterior abdominal wall is a rare complication and reported most often following surgery. To the best of our knowledge, the development of a spontaneous duodenocutaneous fistula in association with duodenal ulcer has only been reported once.

CASE PRESENTATION

A 52-year-old female patient presented at the emergency department with a painful ulcer and erythema on the right abdominal wall. On admission, she was in extremely poor general and nutritional condition. Laboratory analysis revealed inflammation. An empiric antibiotic therapy was initiated; parenteral nutrition, fluid, and electrolyte resuscitation were started. An enterocutaneous fistula was postulated and confirmed by endoscopy identifying a perforated duodenal ulcer. Surgery was not a valuable option and a Foley catheter was inserted through the fistula. During further endoscopic interventions, the Foley catheter was first replaced by a jejunal tube and later by a percutaneous endoscopic gastrostomy with a jejunal limb for enteral nutrition. The fistula output decreased, the local infection was controlled and the nutritional status improved.

CONCLUSIONS

Three months later the fistula was closed and the gastrostomy tube was removed. After 2 years the patient was in good general and nutritional condition.

摘要

目的

十二指肠与前腹壁皮肤之间形成瘘管是一种罕见的并发症,最常于手术后报道。据我们所知,与十二指肠溃疡相关的自发性十二指肠皮肤瘘仅被报道过一次。

病例介绍

一名52岁女性患者因右腹壁疼痛性溃疡和红斑就诊于急诊科。入院时,她的全身和营养状况极差。实验室分析显示有炎症。开始经验性抗生素治疗;同时开始肠外营养、补液及电解质复苏。推测存在肠皮肤瘘,并经内镜检查证实为十二指肠溃疡穿孔。手术并非可行选择,遂经瘘管插入一根 Foley 导管。在进一步的内镜干预过程中,Foley 导管先被空肠管取代,之后又被带有空肠袢的经皮内镜下胃造瘘术取代以进行肠内营养。瘘管排出量减少,局部感染得到控制,营养状况改善。

结论

三个月后瘘管闭合,胃造瘘管拔除。两年后患者全身及营养状况良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05e1/11294516/48ac91385d6f/j_iss-2023-0051_fig_003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05e1/11294516/456f1e83207b/j_iss-2023-0051_fig_001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05e1/11294516/0b39ddce9ba8/j_iss-2023-0051_fig_002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05e1/11294516/48ac91385d6f/j_iss-2023-0051_fig_003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05e1/11294516/456f1e83207b/j_iss-2023-0051_fig_001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05e1/11294516/0b39ddce9ba8/j_iss-2023-0051_fig_002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05e1/11294516/48ac91385d6f/j_iss-2023-0051_fig_003.jpg

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本文引用的文献

1
Closure of a duodenal cutaneous fistula with endoscopic negative pressure therapy using a thin open-pore film drain - an easy tool and simple method.使用薄型开孔薄膜引流管经内镜负压疗法闭合十二指肠皮肤瘘——一种简便的工具和方法
Endoscopy. 2022 Sep;54(9):E490-E491. doi: 10.1055/a-1638-8725. Epub 2021 Oct 8.
2
Prevalence of and Risk Factors for Abdominal Bleeding in Patients with External Duodenal Fistula.患有十二指肠外瘘患者的腹部出血发生率及危险因素。
Med Sci Monit. 2018 Dec 21;24:9317-9323. doi: 10.12659/MSM.912651.
3
Enterocutaneous Fistula From A Billroth II Afferent Limb: Successful Closure With Endoclips.
毕Ⅱ式输入袢肠造口瘘:使用内镜夹成功闭合
ACG Case Rep J. 2014 Jan 10;1(2):76-8. doi: 10.14309/crj.2014.6. eCollection 2014 Jan.
4
An overview of history, pathogenesis and treatment of perforated peptic ulcer disease with evaluation of prognostic scoring in adults.成人穿孔性消化性溃疡疾病的历史、发病机制、治疗概述及预后评分评估
Ann Med Health Sci Res. 2014 Jan;4(1):22-9. doi: 10.4103/2141-9248.126604.
5
[Post-nephrectomy duodeno-cutaneous fistula resolved with parenteral nutrition and octreotide (somatostatin analogue)].[肾切除术后十二指肠皮肤瘘经肠外营养和奥曲肽(生长抑素类似物)治愈]
Arch Esp Urol. 1994 Oct;47(8):810-2.
6
Gastric and duodenal cutaneous fistulas.胃十二指肠皮肤瘘
World J Surg. 1983 Jul;7(4):463-73. doi: 10.1007/BF01655935.
7
Management of Crohn's disease involving the duodenum, including duodenal cutaneous fistula.克罗恩病累及十二指肠的管理,包括十二指肠皮肤瘘。
Arch Surg. 1980 Sep;115(9):1022-8. doi: 10.1001/archsurg.1980.01380090006003.
8
External duodenal fistula. Causes, complications, and treatment.十二指肠外瘘。病因、并发症及治疗
Arch Surg. 1986 Aug;121(8):908-12. doi: 10.1001/archsurg.1986.01400080050009.
9
Spontaneous duodenocutaneous fistula: a rare complication of duodenal ulcer.
Postgrad Med J. 1988 Apr;64(750):328-30. doi: 10.1136/pgmj.64.750.328.