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Time to diversify: germline exome sequencing for men with testicular germ cell tumour.

作者信息

Dholaria Hetal, Tran Ben

机构信息

Department of Paediatric Oncology and Hematology, Perth Children's Hospital, Perth, Australia.

Telethon Kids Cancer Centre, Telethon Kids Institute, Perth, Australia.

出版信息

Transl Androl Urol. 2024 Jul 31;13(7):1329-1332. doi: 10.21037/tau-24-85. Epub 2024 Jun 14.

DOI:10.21037/tau-24-85
PMID:39100820
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11291399/
Abstract
摘要

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Time to diversify: germline exome sequencing for men with testicular germ cell tumour.是时候实现多样化了:对睾丸生殖细胞肿瘤男性患者进行种系外显子组测序。
Transl Androl Urol. 2024 Jul 31;13(7):1329-1332. doi: 10.21037/tau-24-85. Epub 2024 Jun 14.
2
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本文引用的文献

1
The Role of miRNA in Testicular Cancer: Current Insights and Future Perspectives.miRNA 在睾丸癌中的作用:当前的认识和未来的展望。
Medicina (Kaunas). 2023 Nov 17;59(11):2033. doi: 10.3390/medicina59112033.
2
Germline Exome Sequencing for Men with Testicular Germ Cell Tumor Reveals Coding Defects in Chromosomal Segregation and Protein-targeting Genes.胚系外显子组测序揭示了睾丸生殖细胞肿瘤男性中染色体分离和蛋白质靶向基因的编码缺陷。
Eur Urol. 2024 Apr;85(4):337-345. doi: 10.1016/j.eururo.2023.05.008. Epub 2023 May 26.
3
The clinical utility of integrative genomics in childhood cancer extends beyond targetable mutations.
整合基因组学在儿童癌症中的临床应用不仅限于可靶向的突变。
Nat Cancer. 2023 Feb;4(2):203-221. doi: 10.1038/s43018-022-00474-y. Epub 2022 Dec 30.
4
Prospective pan-cancer germline testing using MSK-IMPACT informs clinical translation in 751 patients with pediatric solid tumors.使用MSK-IMPACT进行前瞻性泛癌种胚系检测为751例儿童实体瘤患者的临床转化提供了信息。
Nat Cancer. 2021 Mar;2:357-365. doi: 10.1038/s43018-021-00172-1. Epub 2021 Feb 15.
5
Identification of 22 susceptibility loci associated with testicular germ cell tumors.鉴定与睾丸生殖细胞肿瘤相关的 22 个易感性位点。
Nat Commun. 2021 Jul 23;12(1):4487. doi: 10.1038/s41467-021-24334-y.
6
Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers.基于 14 种癌症常见变异的多基因结构评估和风险预测。
Nat Commun. 2020 Jul 3;11(1):3353. doi: 10.1038/s41467-020-16483-3.
7
Genetics of testicular germ cell tumors.睾丸生殖细胞肿瘤的遗传学
Curr Opin Urol. 2019 Jul;29(4):344-349. doi: 10.1097/MOU.0000000000000642.
8
Variants in BAK1, SPRY4, and GAB2 are associated with pediatric germ cell tumors: A report from the children's oncology group.BAK1、SPRY4和GAB2基因变异与儿童生殖细胞肿瘤相关:来自儿童肿瘤学组的报告
Genes Chromosomes Cancer. 2017 Jul;56(7):548-558. doi: 10.1002/gcc.22457. Epub 2017 Apr 4.
9
Identification of four new susceptibility loci for testicular germ cell tumour.睾丸生殖细胞肿瘤四个新易感基因座的鉴定。
Nat Commun. 2015 Oct 27;6:8690. doi: 10.1038/ncomms9690.
10
Polygenic susceptibility to testicular cancer: implications for personalised health care.睾丸癌的多基因易感性:对个性化医疗的影响。
Br J Cancer. 2015 Nov 17;113(10):1512-8. doi: 10.1038/bjc.2015.334. Epub 2015 Oct 13.