Bandiara Ria, Takaryanto Davin, Andhika Rizky, Makmun Afiatin, Supriyadi Rudi, Sukesi Lilik
Division of Nephrology and Hypertension, Department of Internal Medicine, Padjadjaran University/Hasan Sadikin General Hospital, Bandung, West Java, Indonesia.
Department of Internal Medicine, Padjadjaran University/Hasan Sadikin General Hospital, Bandung, West Java, Indonesia.
Int J Nephrol Renovasc Dis. 2024 Jul 29;17:205-213. doi: 10.2147/IJNRD.S465294. eCollection 2024.
Malnutrition inflammation score (MIS) is an instrument for assessing the nutritional status of stage 5 CKD patients, while simplified creatinine index (SCI) is used to assess muscle mass indirectly.
This study aims to analyse the correlation between SCI and MIS, as well as determine the SCI cut-off value as a predictor of malnutrition in stage 5 CKD patients on maintenance HD.
This research was an analytical observational study with a cross-sectional study approach. The 132 research subjects were stage 5 CKD patients at the HD Unit of RSUP Dr. Hasan Sadikin Bandung. The research used the Rank-Spearman test with SPSS for correlative bivariate analysis. The area under the curve (AUC) on the receiver operating characteristic (ROC) curve was analysed to find the SCI cut-off value as a predictor of malnutrition in stage 5 CKD patients.
Sixty-three subjects (47.7%) were classified as good nutrition and 69 subjects (52.3%) as poor nutrition. The average SCI value in this study was 24.5 mg/kg/day ± SD 3.2 mg/kg/day, with a median MIS value was 6. This study showed a significant negative correlation between SCI and MIS (r = -0.586, p < 0.001). The optimal SCI cut-off from the ROC curve analysis value was ≤ 24.53 mg/kg/day (sensitivity = 76.8%; specificity = 79.4%).
A negative correlation existed between SCI and MIS, with an SCI value ≤ 24.53 indicating poor nutritional status in stage 5 CKD patients on maintenance HD. SCI can be used as a predictor of malnutrition at a lower cost and easier.
营养不良炎症评分（MIS）是评估5期慢性肾脏病（CKD）患者营养状况的一种工具，而简化肌酐指数（SCI）用于间接评估肌肉量。
本研究旨在分析SCI与MIS之间的相关性，并确定SCI的截断值，作为维持性血液透析（HD）的5期CKD患者营养不良的预测指标。
本研究是一项采用横断面研究方法的分析性观察研究。132名研究对象为万隆哈桑·萨迪金博士综合医院血液透析科的5期CKD患者。本研究使用SPSS软件进行Spearman秩相关检验，以进行双变量相关分析。分析受试者工作特征（ROC）曲线下面积（AUC），以确定SCI的截断值，作为5期CKD患者营养不良的预测指标。
63名受试者（47.7%）营养状况良好，69名受试者（52.3%）营养状况较差。本研究中SCI的平均值为24.5mg/kg/天±标准差3.2mg/kg/天，MIS的中位数为6。本研究显示SCI与MIS之间存在显著负相关（r = -0.586，p < 0.001）。ROC曲线分析得出的最佳SCI截断值为≤24.53mg/kg/天（敏感性 = 76.8%；特异性 = 79.4%）。
SCI与MIS之间存在负相关，SCI值≤24.53表明维持性HD的5期CKD患者营养状况较差。SCI可以以更低的成本、更简便地用作营养不良的预测指标。
