Singh Aman G, Alawaed Abdulkhaliq A, Ramachandran P Veeraraghavan
Department of Chemistry, Purdue University West Lafayette IN 47907 USA
RSC Adv. 2024 Aug 2;14(33):24236-24239. doi: 10.1039/d4ra04712e. eCollection 2024 Jul 26.
In contrast to the conversion of diphenylmethanol to the corresponding halides with an equivalent of titanium tetrachloride or -bromide, catalytic (50 mol%) titanium tetrafluoride converts benzhydrols in diethyl ether or dichloromethane to bis(benzhydryl) ethers within 0.5-1 h at room temperature. Cross ether formation with diphenylmethanols and primary aryl or aliphatic alcohols is achieved in the presence of 25 mol% TiF in refluxing toluene as solvent. A tentative mechanism involving a carbocation intermediate has been proposed.
与用等量四氯化钛或四溴化钛将二苯甲醇转化为相应卤化物不同，催化量（50 mol%）的四氟化钛在室温下于0.5 - 1小时内可将二苯甲醇在乙醚或二氯甲烷中转化为双（二苯甲基）醚。在作为溶剂的回流甲苯中，在25 mol% TiF存在下，二苯甲醇与伯芳基或脂肪醇可实现交叉醚化反应。有人提出了一种涉及碳正离子中间体的初步机理。
