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糖化血红蛋白/C 肽水平与诊断为心肌梗死患者短期死亡率的关系。

The association between HbA1c/C-peptide levels and short-term mortality in patients diagnosed with myocardial infarction.

机构信息

Department of Cardiology, Tokat Gaziosmanpaşa University, Tokat, Turkey.

Department of Cardiology, Ministry of Health Sivas Numune Hospital, Sivas, Turkey.

出版信息

Biomark Med. 2024 Aug 17;18(15-16):665-673. doi: 10.1080/17520363.2024.2380248. Epub 2024 Aug 5.

Abstract

In this study, we aimed to investigate the effect of HbA1C/C-peptide ratio on short-term mortality (this period is defined as 30 days after diagnosis) in the patients with myocardial infarction. Around 3245 patients who were admitted due to ST-elevation myocardial infarction (STEMI) and non-ST-elevation myocardial infarction underwent primary percutaneous coronary intervention between October 2020 and 2024 were included in this study. In the receiver operating characteristic analysis, the predictive power of the HCR score for mortality in ST-elevation myocardial infarction patients was determined to be 83% sensitivity and 81% specificity. In non-ST-elevation myocardial infarction, this was determined to be 78% sensitivity and 75% specificity. The HbA1C/C-peptide ratio score can predict poor clinical outcomes early, reducing mortality and morbidity in patients with myocardial infarction.

摘要

在这项研究中,我们旨在研究糖化血红蛋白/ C 肽比值对心肌梗死患者短期死亡率(该期间定义为诊断后 30 天)的影响。本研究共纳入了 3245 名因 ST 段抬高型心肌梗死(STEMI)和非 ST 段抬高型心肌梗死而接受经皮冠状动脉介入治疗的患者。在接受者操作特征分析中,HCR 评分对 ST 段抬高型心肌梗死患者死亡率的预测能力为 83%的敏感性和 81%的特异性。在非 ST 段抬高型心肌梗死中,这一比例分别为 78%的敏感性和 75%的特异性。糖化血红蛋白/ C 肽比值评分可以早期预测不良临床结局,降低心肌梗死患者的死亡率和发病率。

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