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肺泡横纹肌肉瘤的超微结构和免疫组织化学观察

[Ultrastructural and immunohistochemical observations on alveolar rhabdomyosarcoma].

作者信息

Ji Z M

出版信息

Zhonghua Zhong Liu Za Zhi. 1985 Jul;7(4):268-70.

PMID:3910378
Abstract

One case of alveolar rhabdomyosarcoma appearing like an undifferentiated tumor by light microscopy is reported. Specific ultramicroscopic features of sarcomere containing Z line structures, thick and thin myofilaments with hexagonal arrangements in the cross section were noted in the cytoplasm of some individual malignant cells, thus establishing the diagnosis of rhabdomyosarcoma. Some of the tumor cells were positive to peroxidase-anti-peroxidase (PAP) immunohistochemical stain of anti-serum by anti-myosin. In the present paper, the ultrastructural features and differential diagnosis of poorly differentiated rhabdomyosarcoma are also discussed.

摘要

报告1例光镜下表现为未分化肿瘤的肺泡横纹肌肉瘤。在一些单个恶性细胞的细胞质中,观察到含有Z线结构的肌节、粗细肌丝在横切面上呈六边形排列的特异性超微特征,从而确诊为横纹肌肉瘤。部分肿瘤细胞对抗肌球蛋白抗血清的过氧化物酶-抗过氧化物酶(PAP)免疫组化染色呈阳性。本文还讨论了低分化横纹肌肉瘤的超微结构特征及鉴别诊断。

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