十五半综合征 1 例报告。 Notes: 1. 原文中的"fifteen-and-a-half syndrome"直译是“十五半综合征”，但这是一个医学术语，指的是在多种先天性心血管畸形中，同时合并有半月瓣畸形，而房室瓣正常，且半月瓣以单瓣居多。中文中并没有一个通用的术语来翻译这个疾病，因此采用了直译的方式，并在括号内给出了英文缩写。
A case report of fifteen-and-a-half syndrome.
机构信息
Department of Neurology, Weifang people's hospital, Shandong Second Medical University, 151 Guangwen Street, Weifang, 261000, Shandong, China.
Department of Food Nutrition and Student Health, Center for Disease Control and Prevention, 4801 Huixian Road, Weifang, 261061, Shandong, China.
出版信息
BMC Neurol. 2024 Aug 5;24(1):273. doi: 10.1186/s12883-024-03784-z.
BACKGROUND
Fifteen-and-a-Half Syndrome is an uncommon clinical presentation characterized by the coexistence of one-and-a-half syndrome and bilateral facial palsy. In this study, we provide a comprehensive description of symptom evolution and imaging changes in a patient with Fifteen-and-a-Half Syndrome.
CASE PRESENTATION
A 54-year-old male presented with sudden onset of one-and-a-half syndrome, which gradually progressed to fifteen-and-a-half syndrome. The final diagnosis was confirmed to be pontine infarction which occurred at the midline of the pontine tegmentum.
CONCLUSION
This case highlights the diverse and progressive early clinical manifestations associated with Fifteen-and-a-half Syndrome. Currently, all reported cases of this syndrome are linked to brainstem infarction; however, early differential diagnosis is crucial to ensure prompt initiation of appropriate treatment for affected patients.
背景
十五半综合征是一种罕见的临床病症，其特征为存在一半半综合征和双侧面瘫。本研究提供了一位十五半综合征患者的症状演变和影像学改变的全面描述。
病例介绍
一位 54 岁男性突发出现一半半综合征，逐渐进展为十五半综合征。最终诊断为桥脑被盖中线处的桥脑梗死。
结论
本病例强调了十五半综合征相关的多样化和进展性的早期临床表现。目前，所有报告的该综合征病例均与脑干梗死相关；然而，早期鉴别诊断至关重要，以确保对受累患者及时开始适当的治疗。
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