Department of Neurology, Weifang people's hospital, Shandong Second Medical University, 151 Guangwen Street, Weifang, 261000, Shandong, China.
Department of Food Nutrition and Student Health, Center for Disease Control and Prevention, 4801 Huixian Road, Weifang, 261061, Shandong, China.
BMC Neurol. 2024 Aug 5;24(1):273. doi: 10.1186/s12883-024-03784-z.
Fifteen-and-a-Half Syndrome is an uncommon clinical presentation characterized by the coexistence of one-and-a-half syndrome and bilateral facial palsy. In this study, we provide a comprehensive description of symptom evolution and imaging changes in a patient with Fifteen-and-a-Half Syndrome.
A 54-year-old male presented with sudden onset of one-and-a-half syndrome, which gradually progressed to fifteen-and-a-half syndrome. The final diagnosis was confirmed to be pontine infarction which occurred at the midline of the pontine tegmentum.
This case highlights the diverse and progressive early clinical manifestations associated with Fifteen-and-a-half Syndrome. Currently, all reported cases of this syndrome are linked to brainstem infarction; however, early differential diagnosis is crucial to ensure prompt initiation of appropriate treatment for affected patients.
十五半综合征是一种罕见的临床病症，其特征为存在一半半综合征和双侧面瘫。本研究提供了一位十五半综合征患者的症状演变和影像学改变的全面描述。
一位 54 岁男性突发出现一半半综合征，逐渐进展为十五半综合征。最终诊断为桥脑被盖中线处的桥脑梗死。
本病例强调了十五半综合征相关的多样化和进展性的早期临床表现。目前，所有报告的该综合征病例均与脑干梗死相关；然而，早期鉴别诊断至关重要，以确保对受累患者及时开始适当的治疗。
