Varis Heidi, Heikkala Eveliina, Mikkola Ilona, Nordström Tanja, Taanila Anja, Keinänen-Kiukaanniemi Sirkka, Hagnäs Maria
Research Unit of Population Health, University of Oulu, Finland.
Wellbeing Services, County of Lapland, Rovaniemi, Finland.
Scand J Public Health. 2024 Aug 6:14034948241260765. doi: 10.1177/14034948241260765.
This longitudinal study evaluated the association between childhood family structure and health-related quality of life (HRQoL) at middle age.
The data on childhood family structure at the age of 14 years ('two-parent family', 'one parent not living at home/no information on father' and 'father or mother deceased') and HRQoL (measured by 15D (15-dimensional)) at the age of 46 were collected from the Northern Finland Birth Cohort 1966 using postal questionnaires. We used the binary logistic regression model to estimate the associations between childhood family structures and the lowest 15D quartile (reference: all other quartiles). The associations were adjusted for offspring mothers' factors during pregnancy (mothers' educational and occupational status).
Of the 6375 participants, the offspring belonging to the 'one parent not living at home/no information on father' family structure subgroup had higher odds ratio of belonging to the lowest 15D quartile than the offspring of 'two-parent families' (adjusted odds ratio (OR) 1.76, 95% confidence interval (CI) 1.31-2.36, p<0.001 for females; adjusted OR 1.86, 95% CI 1.28-2.70, p=0.001 for males). There were no statistically significant associations between the 'father or mother deceased' subgroup and the lowest 15D quartile among the offspring.
A single-parent family origin (due to reasons other than parental death) in childhood was significantly associated with impaired HRQoL at middle age. These results provide new perspectives for understanding the long-standing associations on living in a single-parent family.
本纵向研究评估了儿童期家庭结构与中年时健康相关生活质量（HRQoL）之间的关联。
通过邮政问卷从1966年芬兰北部出生队列中收集了14岁时儿童期家庭结构的数据（“双亲家庭”、“一方父母不住在家中/无父亲信息”和“父亲或母亲已故”）以及46岁时的HRQoL（用15D量表（15维度）测量）。我们使用二元逻辑回归模型来估计儿童期家庭结构与15D量表最低四分位数之间的关联（参照：所有其他四分位数）。这些关联针对孕期母亲的因素（母亲的教育和职业状况）进行了调整。
在6375名参与者中，属于“一方父母不住在家中/无父亲信息”家庭结构亚组的后代比“双亲家庭”的后代属于15D量表最低四分位数的优势比更高（女性调整后的优势比（OR）为1.76，95%置信区间（CI）为1.31 - 2.36，p < 0.001；男性调整后的OR为1.86，95% CI为1.28 - 2.70，p = 0.001）。在后代中，“父亲或母亲已故”亚组与15D量表最低四分位数之间没有统计学上的显著关联。
儿童期单亲家庭出身（因父母死亡以外的原因）与中年时HRQoL受损显著相关。这些结果为理解单亲家庭生活的长期关联提供了新的视角。
