Sun Yan-Ni, Zhao Lei, Liu Wei, Yin Xiao-Ping
Department of Stomatology, Qingdao Hiser Hospital, Affiliated to Qingdao University(Qingdao Traditional Chinese Medicine Hospital). Qingdao 266000, China. E-mail:
Shanghai Kou Qiang Yi Xue. 2024 Jun;33(3):260-264.
To explore the effect of using iRoot BP plus and MTA apical barrier surgery in young permanent teeth with chronic apical periodontitis.
A total of 122 patients with chronic periapical periodontitis with open root tips of permanent teeth were randomly divided into experimental group (n=61, 61 teeth) and a control group (n=61, 61 teeth). Patients in the experimental group received iRoot BP plus plus apical barrier surgery, while those in the control group received MTA apical barrier surgery. The old periapical index (O-PAI), apical transmission area, efficacy, treatment times, and inflammatory factor levels of the two groups of patients were compared at 3, 6, 9, and 12 months after surgery. SPSS 19.0 software package was used for statistical analysis.
At 12 months after surgery, the O-PAI ratings of the experimental group and the control group were (1.48±0.36) and (1.71±0.42), respectively, and the apical transmission area was (0.51±0.14) and (1.09±0.31). There was a significant difference in the O-PAI ratings and apical transmission area between the two groups(P＜0.05). At 3 months, 6 months, and 12 months after surgery, the O-PAI scores of patients in both groups gradually decreased (P＜0.05). After 12 months of treatment, the success rates of the experimental group and the control group were 98.36% and 88.52%, respectively, with significant difference between the two groups (P＜0.05). The treatment frequency of patients in the experimental group and the control group was (3.64±0.58) times and (4.72±0.61) times, respectively, with a significant difference between the two groups(P＜0.05). After 3 months of treatment, the serum hs-CRP levels in the experimental group and the control group were (6.89±1.13) mg/L and (7.25±1.40) mg/L, respectively, with a significant difference compared to pre-treatment(P＜0.05). After 3 months of treatment, the serum IL-6 levels in the experimental group and the control group were (82.04±19.62) mg/L and (87.52±20.85) mg/L, respectively, with significant differences compared to pre-treatment (P＜0.05). There was no significant difference in serum IL-6 and hs-CRP levels between the two groups before and after treatment(P＞0.05).
iRoot BP plus apical barrier surgery for the treatment of chronic apical periodontitis with open permanent teeth can reduce the O-PAI index, decrease the number of postoperative visits, and have a higher postoperative success rate.
探讨使用iRoot BP plus和MTA进行根尖屏障术治疗年轻恒牙慢性根尖周炎的效果。
将122例恒牙牙根开放的慢性根尖周炎患者随机分为试验组（n = 61，61颗牙）和对照组（n = 61，61颗牙）。试验组患者接受iRoot BP plus根尖屏障术，而对照组患者接受MTA根尖屏障术。比较两组患者术后3、6、9和12个月时的旧根尖指数（O-PAI）、根尖透射区、疗效、治疗次数及炎症因子水平。采用SPSS 19.0软件包进行统计分析。
术后12个月时，试验组和对照组的O-PAI评分分别为（1.48±0.36）和（1.71±0.42），根尖透射区分别为（0.51±0.14）和（1.09±0.31）。两组间O-PAI评分及根尖透射区差异有统计学意义（P＜0.05）。术后3、6和12个月时，两组患者的O-PAI评分均逐渐降低（P＜0.05）。治疗12个月后，试验组和对照组的成功率分别为98.36%和88.52%，两组间差异有统计学意义（P＜0.05）。试验组和对照组患者的治疗次数分别为（3.64±0.58）次和（4.72±0.61）次，两组间差异有统计学意义（P＜0.05）。治疗3个月后，试验组和对照组血清hs-CRP水平分别为（6.89±1.13）mg/L和（7.25±1.40）mg/L，与治疗前相比差异有统计学意义（P＜0.05）。治疗3个月后，试验组和对照组血清IL-6水平分别为（82.04±19.62）mg/L和（87.52±20.85）mg/L，与治疗前相比差异有统计学意义（P＜0.05）。两组治疗前后血清IL-6和hs-CRP水平差异无统计学意义（P＞0.05）。
iRoot BP plus根尖屏障术治疗恒牙牙根开放的慢性根尖周炎可降低O-PAI指数，减少术后复诊次数，术后成功率更高。
