• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Single-cell analyses revealed key tumor-infiltrating myeloid cell subsets associated with clinical outcomes in different subtypes of breast cancer.

作者信息

Wu Dingjie, Chen Si, Liu Yijin, Yang Bowen, Li Ruixin, Jin Feng, Yao Fan, Fang Yue

机构信息

Department of Microbial and Biochemical Pharmacy, School of Pharmacy, China Medical University, Shenyang, Liaoning 110122, China.

Department of Breast Surgery and Surgical Oncology, Research Unit of General Surgery, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110000, China.

出版信息

Genes Dis. 2023 Nov 30;11(6):101185. doi: 10.1016/j.gendis.2023.101185. eCollection 2024 Nov.

DOI:10.1016/j.gendis.2023.101185
PMID:39104420
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11298853/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e590/11298853/a45746e74721/figs6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e590/11298853/dfe133699ad3/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e590/11298853/1819366a96a4/figs1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e590/11298853/eca510518a4b/figs2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e590/11298853/6b7867038271/figs3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e590/11298853/318c519931dc/figs4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e590/11298853/744f1669409e/figs5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e590/11298853/a45746e74721/figs6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e590/11298853/dfe133699ad3/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e590/11298853/1819366a96a4/figs1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e590/11298853/eca510518a4b/figs2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e590/11298853/6b7867038271/figs3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e590/11298853/318c519931dc/figs4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e590/11298853/744f1669409e/figs5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e590/11298853/a45746e74721/figs6.jpg

相似文献

1
Single-cell analyses revealed key tumor-infiltrating myeloid cell subsets associated with clinical outcomes in different subtypes of breast cancer.单细胞分析揭示了与不同亚型乳腺癌临床结局相关的关键肿瘤浸润髓样细胞亚群。
Genes Dis. 2023 Nov 30;11(6):101185. doi: 10.1016/j.gendis.2023.101185. eCollection 2024 Nov.
2
Evaluation of tumor immune contexture among intrinsic molecular subtypes helps to predict outcome in early breast cancer.评估早期乳腺癌内在分子亚型中的肿瘤免疫微环境有助于预测预后。
J Immunother Cancer. 2021 Jun;9(6). doi: 10.1136/jitc-2020-002036.
3
Infiltrating myeloid cell diversity determines oncological characteristics and clinical outcomes in breast cancer.浸润性髓样细胞多样性决定乳腺癌的肿瘤学特征和临床结局。
Breast Cancer Res. 2023 Jun 7;25(1):63. doi: 10.1186/s13058-023-01669-6.
4
Heterogeneity of tumor-infiltrating myeloid cells in era of single-cell genomics.单细胞基因组学时代肿瘤浸润髓系细胞的异质性
Chin J Cancer Res. 2022 Dec 30;34(6):543-553. doi: 10.21147/j.issn.1000-9604.2022.06.01.
5
Tumour-Infiltrating Immune Cell-Based Subtyping and Signature Gene Analysis in Breast Cancer Based on Gene Expression Profiles.基于基因表达谱的乳腺癌肿瘤浸润免疫细胞亚型分类及特征基因分析
J Cancer. 2020 Jan 14;11(6):1568-1583. doi: 10.7150/jca.37637. eCollection 2020.
6
Immunity and Extracellular Matrix Characteristics of Breast Cancer Subtypes Based on Identification by T Helper Cells Profiling.基于辅助性 T 细胞分析鉴定的乳腺癌亚型的免疫和细胞外基质特征。
Front Immunol. 2022 Jun 20;13:859581. doi: 10.3389/fimmu.2022.859581. eCollection 2022.
7
Identification of tumour-infiltrating myeloid subsets associated with overall survival in lung squamous cell carcinoma.鉴定与肺鳞癌总生存期相关的肿瘤浸润髓系亚群。
J Pathol. 2023 Jan;259(1):21-34. doi: 10.1002/path.6015. Epub 2022 Nov 16.
8
Bulk and Single-Cell Profiling of Breast Tumors Identifies TREM-1 as a Dominant Immune Suppressive Marker Associated With Poor Outcomes.乳腺肿瘤的整体和单细胞分析确定TREM-1是与不良预后相关的主要免疫抑制标志物。
Front Oncol. 2021 Dec 8;11:734959. doi: 10.3389/fonc.2021.734959. eCollection 2021.
9
A Proteomic Atlas of Lineage and Cancer-Polarized Expression Modules in Myeloid Cells Modeling Immunosuppressive Tumor-Infiltrating Subsets.髓系细胞中模拟免疫抑制性肿瘤浸润亚群的谱系和癌症极化表达模块的蛋白质组图谱
J Pers Med. 2021 Jun 11;11(6):542. doi: 10.3390/jpm11060542.
10
Interleukin-6 receptor and its ligand interleukin-6 are opposite markers for survival and infiltration with mature myeloid cells in ovarian cancer.白细胞介素 6 受体及其配体白细胞介素 6 是卵巢癌中存活和成熟髓样细胞浸润的相反标志物。
Oncoimmunology. 2015 Jan 7;3(12):e962397. doi: 10.4161/21624011.2014.962397. eCollection 2014 Dec.

引用本文的文献

1
Exploring the Molecular Functions and Immune Relevance of Macrophage-Associated Genes in Atherosclerosis.探索动脉粥样硬化中巨噬细胞相关基因的分子功能及免疫相关性
Hum Mutat. 2025 Aug 20;2025:9034896. doi: 10.1155/humu/9034896. eCollection 2025.
2
IGLL5 has potential to be a prognostic biomarker and its correlation with immune infiltrates in breast cancer.IGLL5有潜力成为一种预后生物标志物及其与乳腺癌免疫浸润的相关性。
Am J Clin Exp Immunol. 2025 Jun 15;14(3):111-126. doi: 10.62347/XLCY5727. eCollection 2025.

本文引用的文献

1
A pan-cancer single-cell transcriptional atlas of tumor infiltrating myeloid cells.泛癌种肿瘤浸润髓系细胞的单细胞转录组图谱。
Cell. 2021 Feb 4;184(3):792-809.e23. doi: 10.1016/j.cell.2021.01.010.
2
Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries.《全球癌症统计数据 2020:全球 185 个国家和地区 36 种癌症的发病率和死亡率估计》。
CA Cancer J Clin. 2021 May;71(3):209-249. doi: 10.3322/caac.21660. Epub 2021 Feb 4.
3
CCL4 Signaling in the Tumor Microenvironment.四氯化碳信号在肿瘤微环境中的作用。
Adv Exp Med Biol. 2020;1231:23-32. doi: 10.1007/978-3-030-36667-4_3.
4
Landscape and Dynamics of Single Immune Cells in Hepatocellular Carcinoma.肝癌中单免疫细胞的景观和动态。
Cell. 2019 Oct 31;179(4):829-845.e20. doi: 10.1016/j.cell.2019.10.003.
5
Expression profiling of constitutive mast cells reveals a unique identity within the immune system.组成型肥大细胞的表达谱揭示了其在免疫系统中的独特特性。
Nat Immunol. 2016 Jul;17(7):878-87. doi: 10.1038/ni.3445. Epub 2016 May 2.