Amadi Hippolite O, Abioye Ifeoluwa O, Ugbolue Ukadike C, Ekpenyong Rhoda-Dara, Ekwem Nnamdi F, Nwaneri Ogechi J, Dike Chidiebere
Department of Bioengineering, Imperial College London, London, United Kingdom.
Division of Precision Health, Quality and Safety Leadership, University of Calgary, Alberta, AB, Canada.
Front Pediatr. 2024 Jul 22;12:1413113. doi: 10.3389/fped.2024.1413113. eCollection 2024.
The high neonatal mortality rate in low- and middle-income countries (LMICs) such as Nigeria has lasted for more than 30 years to date with associated nursing fatigue. Despite prominent hard work, technological improvements, and many publications released from the country since 1990, the problem has persisted, perhaps due to a lack of intervention scale-up. Could there be neglected discoveries unwittingly abandoned by Nigerian policymakers over the years, perhaps locked up in previous publications? A careful review may reveal these insights to alert policymakers, inspire researchers, and refocus in-country research efforts towards impactful directions for improving neonatal survival rates. The focus was to determine the prevailed effectiveness of LMIC medical academia in creating solutions to end the high neonatal mortality rate.
An unconventional systematic review protocol structure following the PRISMA 2020 checklist was designed and registered at INPLASY (registration number: INPLASY202380096, doi: 10.37766/inplasy2023.8.0096). A jury of paediatricians was assembled and observed by a team of legal professionals. The jury searched the literature from 1990 to the end of 2022, extracted newborn-related articles about Nigeria, and assessed and debated them against expected criteria for solution creation, translation, scale-up, sustainability, and national coverage. Each juror used preset criteria to produce a verdict on the possibility of a published novel idea being a potential game-changer for improving the survival rate of Nigerian neonates.
A summation of the results showed that 19 out of 4,286 publications were assessed to possess potential strategies or interventions to reduce neonatal mortality. Fourteen were fully developed but not appropriately scaled up across the country, hence denying neonates proper access to these interventions.
Nigeria may already have the required game-changing ideas to strategically scale up across the nation to accelerate neonatal survival. Therefore, LMIC healthcare systems may have to look inward to strengthen what they already possess.
https://inplasy.com/, identifier (INPLASY202380096).
在尼日利亚等低收入和中等收入国家(LMICs),新生儿死亡率居高不下的情况至今已持续了30多年,这也导致了护理人员的疲劳。自1990年以来,尽管该国付出了巨大努力、技术有所进步且发表了许多文献,但这个问题依然存在,可能是由于缺乏干预措施的扩大推广。多年来,尼日利亚的政策制定者是否无意中忽略了一些被放弃的发现,也许它们被尘封在以前的出版物中?仔细回顾可能会揭示这些见解,以提醒政策制定者、激励研究人员,并将国内的研究工作重新聚焦于提高新生儿存活率的有效方向。重点是确定低收入和中等收入国家医学学术界在创造解决方案以终结高新生儿死亡率方面的普遍有效性。
设计了一种遵循PRISMA 2020清单的非常规系统评价方案结构,并在INPLASY注册(注册号:INPLASY202380096,doi: 10.37766/inplasy2023.8.0096)。组建了一个儿科医生评审团,并由一组法律专业人员进行监督。评审团检索了1990年至2022年底的文献,提取了与尼日利亚新生儿相关的文章,并根据解决方案的创建、翻译、扩大推广、可持续性和全国覆盖范围的预期标准对其进行评估和辩论。每位评审员使用预设标准对已发表的新想法成为改善尼日利亚新生儿存活率的潜在变革性因素的可能性做出裁决。
结果汇总显示,在4286篇出版物中,有19篇被评估为具有降低新生儿死亡率的潜在策略或干预措施。其中14项已充分开发,但未在全国范围内适当扩大推广,因此新生儿无法获得这些干预措施。
尼日利亚可能已经拥有在全国范围内进行战略推广以加速新生儿存活所需的变革性想法。因此,低收入和中等收入国家的医疗保健系统可能需要审视自身,加强已有的资源。