Dos Anjos Renata Tulio Küster Bernardo, Engracia Maria Julia Gracioli, Etgeton Schaina Andriela Pontarollo, Silva Rodrigues Aline Danielle Di Paula, Rodrigues Silva Anne Caroline, Krüger Cláudia Carneiro Hecke, Turnes Pasini Deolindo Carolina, Hoff Rodrigo Barcellos, Barreto Fabiano, Moresco Karla Suzana, Ávila Suelen, Rodrigues Ferreira Sila Mary
Postgraduate Program in Food and Nutrition, Federal University of Paraná, Curitiba, Brazil.
Graduate Program in Nutrition, Federal University of Paraná, Curitiba, Brazil.
Nat Prod Res. 2024 Aug 6:1-9. doi: 10.1080/14786419.2024.2385033.
Quality control of propolis plays a pivotal role in ensuring the appropriate concentrations of active compounds, limiting unwanted substances, verifying authenticity, and adhering to regulatory standards. This study aimed to assess the identity and quality standards, the individual phenolic composition (LC-ESI-MS/MS), and the antioxidant and antiglycemic potential of commercial propolis extracts (CPEs) from , , and bees. CPEs met wax content and oxidation activity criteria, surpassing minimum thresholds for total phenolic content (TPC) and flavonoid content (TFC), although stingless bee CPE did not test positive for 10% lead acetate. CPEs exhibited antioxidant and potential antiglycemic activities. Epicatechin among the thirty-three identified phenolics, showed significant correlation with TPC, DPPH, ABTS, and EC50 values of α-amylase enzyme. These promising attributes underscore the potential health benefits of commercial propolis extracts from and stingless bees for further medicinal and nutritional applications.
蜂胶的质量控制在确保活性化合物的适当浓度、限制有害物质、验证真伪以及遵守监管标准方面起着关键作用。本研究旨在评估来自[具体蜜蜂种类1]、[具体蜜蜂种类2]和无刺蜂的商业蜂胶提取物（CPEs）的特性和质量标准、单个酚类成分（LC-ESI-MS/MS）以及抗氧化和抗血糖潜力。CPEs符合蜡含量和氧化活性标准，总酚含量（TPC）和类黄酮含量（TFC）超过最低阈值，尽管无刺蜂CPE对10%醋酸铅检测呈阴性。CPEs表现出抗氧化和潜在的抗血糖活性。在鉴定出的33种酚类物质中，表儿茶素与TPC、DPPH、ABTS以及α-淀粉酶的EC50值显示出显著相关性。这些有前景的特性突出了来自[具体蜜蜂种类1]和无刺蜂的商业蜂胶提取物在进一步医药和营养应用方面的潜在健康益处。
