Beijing Tongren Eye Center, Beijing Ophthalmology and Visual Science Key Lab, Beijing Key Laboratory of Intraocular Tumor Diagnosis and Treatment, Capital Medical University, Beijing Tongren Hospital, Beijing, China.
Diab Vasc Dis Res. 2024 Jul-Aug;21(4):14791641241271899. doi: 10.1177/14791641241271899.
The aim of this study was to analyze the incidence of retinal vein occlusion (RVO) in patients with and without diabetes in the population and compare the influencing factors.
The community-based Kailuan Eye Study included 14,440 participants (9835 male, 4605 female) with a mean age of 54.0 ± 13.3 years (range, 20-110 years). They underwent a systemic and ophthalmologic examination. RVO were diagnosed on fundus photographs.
By matching for age and gender, we included a total of 2767 patients each with diabetes and non-diabetes. The prevalence of RVO among patients with and without diabetes was 1.5% and 0.8%, respectively. The prevalence of RVO was higher in patients with diabetes than in patients without diabetes in all age groups. Multifactorial regression analysis showed that only fasting blood glucose levels were significantly different between patients with RVO with or without DM. The occurrence of RVO in the group with diabetes was mainly associated with higher fasting glucose and systolic blood pressure; in the group without diabetes, RVO was mainly associated with higher diastolic blood pressure, Body Mass Index, and lower low-density lipoprotein cholesterol levels.
We found that patients with diabetes have increased risks of RVO. In addition to blood pressure control, we recommend educating patients with diabetes about RVO, to prevent its subsequent occurrence.
本研究旨在分析人群中伴或不伴糖尿病的视网膜静脉阻塞（RVO）的发病率，并比较其影响因素。
基于社区的开滦眼病研究纳入了 14440 名参与者（9835 名男性，4605 名女性），平均年龄为 54.0±13.3 岁（范围 20-110 岁）。他们接受了系统的眼科检查。RVO 通过眼底照片诊断。
通过年龄和性别匹配，我们共纳入了 2767 例糖尿病患者和 2767 例非糖尿病患者。有糖尿病和无糖尿病患者的 RVO 患病率分别为 1.5%和 0.8%。在所有年龄组中，糖尿病患者的 RVO 患病率均高于无糖尿病患者。多因素回归分析显示，仅空腹血糖水平在有或无 DM 的 RVO 患者之间存在显著差异。糖尿病组 RVO 的发生主要与较高的空腹血糖和收缩压有关；在非糖尿病组中，RVO 主要与较高的舒张压、体重指数和较低的低密度脂蛋白胆固醇水平有关。
我们发现糖尿病患者 RVO 的风险增加。除了控制血压外，我们还建议对糖尿病患者进行 RVO 的教育，以预防其后续发生。
