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魔力Touch 西罗莫司涂层球囊:冠状动脉西罗莫司药物涂层球囊的动物和临床证据。

Magic Touch sirolimus-coated balloon: animal and clinical evidence of a coronary sirolimus drug-coated balloon.

机构信息

Fondazione Ricerca e Innovazione Cardiovascolare, Milano, Italy.

DCB Academy, Milano, Italy.

出版信息

Future Cardiol. 2024;20(10):521-535. doi: 10.1080/14796678.2024.2345023. Epub 2024 Aug 6.

Abstract

The Magic Touch sirolimus-coated balloon (SCB) was recently introduced in Europe and features robust clinical technology different from other devices on the market. This device is able to deliver a sufficient sirolimus dose to the target segment to reduce neointimal proliferation with very little exposure downstream and no apparent adverse effects at sustained high drug concentrations. The SCB represents a promising novelty within the drug-coated balloon arena due to its mid-term efficacy and safety in the treatment of coronary artery disease, especially in and small-vessel coronary lesions. The purpose of this article is to provide an up-to-date overview of the currently available animal and clinical trial results, as well as to highlight ongoing trials on the Magic Touch SCB.

摘要

魔力-touch 西罗莫司涂层球囊(SCB)最近在欧洲推出,具有与市场上其他设备不同的强大临床技术。该设备能够向目标节段输送足够的西罗莫司剂量,以减少新生内膜增殖,同时下游暴露量非常少,在持续高药物浓度下也没有明显的不良反应。由于其在治疗冠状动脉疾病,特别是在和小血管冠状动脉病变中的中期疗效和安全性,SCB 代表了药物涂层球囊领域的一个有前途的新进展。本文旨在提供最新的动物和临床试验结果综述,并强调正在进行的关于 Magic Touch SCB 的试验。

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