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用于鼻源性头痛的向心性鼻窦内窥镜手术

Centripetal endoscopic sinus surgery in rhinogenic headache.

作者信息

Cascio Filippo, d'Alcontres Ferdinando Stagno, Costanzo Daria, Nicastro Viviana, Stolfa Andrea, Clemenzi Veronica, Sireci Federico, Lorusso Francesco, Felippu Andrè Wady Debes, Felippu Alex Wady Debes, Cascio Felice, Gazia Francesco

机构信息

AO Papardo, Unit of Otorhinolaryngology, Messina, Italy.

Department of Sensorial Organs, ENT Section, "Sapienza" University of Rome, Rome, Italy.

出版信息

Am J Otolaryngol. 2024 Nov-Dec;45(6):104473. doi: 10.1016/j.amjoto.2024.104473. Epub 2024 Aug 2.

Abstract

OBJECTIVES

The aim of this manuscript is to analyse a diagnostic protocol to select correctly patients with Rhinogenic Headache Contact Point (RH) and to investigate the effect of surgical treatment and medical therapy in pain relief.

METHODS

A prospective no-randomized study selected adult patients with headache and nasal alteration at CT exam or endoscopic vision with positive response to test with nasal spray with corticosteroids and antihistamine or/and local anesthesia test to the contact points. MIDAS score, intensity score, daily duration of symptoms, frequency of headache in the last month were collected in patients who performed surgery and in patients who performed medical therapy.

RESULTS

Following the inclusion, 415 patients were selected for this study. 302 patients performed nasal surgery (septoplasty, turbinoplasty and/or endoscopic surgery with centripetal technique), 113 performed medical therapy. There was a statistically significant improvement in MIDAS score, intensity score, daily duration of symptoms, frequency of headache in the last month in patients who performed surgery and in patients who performed medical therapy. Regarding the comparison between patients who performed surgery (Group A) and patients who performed only medical therapy for RH (Group B), better outcomes were obtained by Group A. Considering the daily life handicap index, the lowest handicap was obtained in Group A.

CONCLUSION

This study demonstrates that surgery, using in some cases centripetal technique, gives an improvement statistically significant than medical therapy in RH. The use of nasal spray with corticosteroids and with anti-histamine is a good method in the diagnosis of RH, especially in patients with anatomical variants such as concha bullosa, agger nasi cells and Haller cells.

摘要

目的

本手稿旨在分析一种诊断方案,以正确筛选出患有鼻源性头痛接触点(RH)的患者,并研究手术治疗和药物治疗在缓解疼痛方面的效果。

方法

一项前瞻性非随机研究选取了在CT检查或内镜检查中有头痛和鼻腔改变的成年患者,这些患者对使用皮质类固醇和抗组胺药的鼻喷雾剂试验或/和对接触点的局部麻醉试验有阳性反应。收集了接受手术治疗的患者和接受药物治疗的患者的偏头痛残疾评定量表(MIDAS)评分、强度评分、症状每日持续时间、过去一个月内头痛频率。

结果

纳入研究后,共选取了415例患者。302例患者接受了鼻腔手术(鼻中隔成形术、鼻甲成形术和/或采用向心性技术的内镜手术),113例患者接受了药物治疗。接受手术治疗的患者和接受药物治疗的患者在MIDAS评分、强度评分、症状每日持续时间、过去一个月内头痛频率方面均有统计学意义的改善。关于接受手术治疗的患者(A组)和仅接受RH药物治疗的患者(B组)之间的比较,A组获得了更好的结果。考虑到日常生活障碍指数,A组的障碍最低。

结论

本研究表明,在某些情况下采用向心性技术的手术治疗在RH方面比药物治疗有统计学意义的改善。使用含有皮质类固醇和抗组胺药的鼻喷雾剂是诊断RH的一种好方法,特别是对于患有诸如泡状鼻甲、鼻丘气房和Haller气房等解剖变异的患者。

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