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疟疾后儿童带状疱疹

Herpes zoster in children following malaria.

作者信息

Cook I F

出版信息

J Trop Med Hyg. 1985 Aug;88(4):261-4.

PMID:3910848
Abstract

Herpes zoster is uncommon in normal children in the 0-9 year age group. However, its incidence is markedly increased in those who are immunosuppressed. Six Papua New Guinean children under 9 years of age developed herpes zoster following an episode of malaria, due to Plasmodium falciparum or Plasmodium vivax which was treated with chloroquine. The reactivation of the varicella-zoster virus in these patients may reflect transient depression of cell-mediated immunity by these malaria parasites, possibly augmented by the chloroquine used in their treatment.

摘要

带状疱疹在0至9岁的正常儿童中并不常见。然而,在免疫功能低下的儿童中,其发病率显著增加。六名9岁以下的巴布亚新几内亚儿童在患疟疾病例后出现带状疱疹,这些疟疾由恶性疟原虫或间日疟原虫引起,并用氯喹进行了治疗。这些患者水痘-带状疱疹病毒的重新激活可能反映了这些疟原虫对细胞介导免疫的短暂抑制,其治疗中使用的氯喹可能加剧了这种抑制。

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