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罕见的原发性结肠T细胞淋巴瘤经内镜黏膜下剥离术根治性切除:1例报告

Rare primary colonic T cell lymphoma with curative resection by endoscopic submucosal dissection: A case report.

作者信息

Sun Yu-Hui, Lu Shuang-Shuang, Fang Ying, Xiong Zhe, Sun Qiu-Yue, Huang Jin

机构信息

Nanjing Medical University, The Affiliated Changzhou Second People's Hospital of Nanjing Medical University, Changzhou 213000, Jiangsu Province, China.

Gastroenterology Center, The Affiliated Changzhou Second People's Hospital of Nanjing Medical University, Changzhou 213000, Jiangsu Province, China.

出版信息

World J Clin Cases. 2024 Aug 6;12(22):5229-5235. doi: 10.12998/wjcc.v12.i22.5229.

Abstract

BACKGROUND

The gastrointestinal tract is a well-known extranodal site of lymphoma. B-cell lymphoma is the most common type, while T-cell lymphoma is uncommon. Primary gastrointestinal lymphoma mainly occurs in the stomach and small intestine, and the colon is less frequently involved, especially in females.

CASE SUMMARY

A 45-year-old woman was admitted to our hospital for physical examination. Gastroenteroscopy revealed a visible pedunculated polyp in the transverse colon, for which endoscopic submucosal dissection (ESD) was performed. Pathology suggested highly active proliferation of T lymphocytes with atypical hyperplasia.

CONCLUSION

A middle-aged female patient was found to have colonic T-cell lymphoma by endoscopy. The lesion was successfully removed by ESD, and the surgical margin was negative. It is essential to raise awareness of colonic T-cell lymphoma and choose the appropriate treatment.

摘要

背景

胃肠道是淋巴瘤常见的结外受累部位。B细胞淋巴瘤是最常见的类型,而T细胞淋巴瘤并不常见。原发性胃肠道淋巴瘤主要发生在胃和小肠,结肠受累较少,尤其是女性。

病例摘要

一名45岁女性因体检入院。胃镜检查发现横结肠有一个带蒂息肉,遂行内镜下黏膜剥离术(ESD)。病理提示T淋巴细胞高度活跃增殖伴非典型增生。

结论

一名中年女性患者经内镜检查发现结肠T细胞淋巴瘤。病变通过ESD成功切除,手术切缘阴性。提高对结肠T细胞淋巴瘤的认识并选择合适的治疗方法至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0e7/11238787/1eb7573d327d/WJCC-12-5229-g001.jpg

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