Yang Si-Yun, Wang Jin-Zhu, Fan Hao, Chen Min
Department of Stomatology, Anhui Jieshou People's Hospital, Fuyang 236500, Anhui Province, China.
Department of Stomatology, Jiangsu Yancheng Maternal and Child Health Hospital, Yancheng 224000, Jiangsu Province, China.
World J Clin Cases. 2024 Aug 6;12(22):5024-5031. doi: 10.12998/wjcc.v12.i22.5024.
The role of epinephrine in the treatment of pulp capping in patients with reversible pulpitis is not clear.
To explore the role of epinephrine in the treatment of pulp capping in patients with reversible pulpitis.
A total of 100 patients with reversible pulpitis who were treated in Anhui Jieshou People's Hospital from January 2020 to December 2021 were included in the study. They were categorized into an observation group ( = 50; treatment with adrenaline) and a control group ( = 50; treatment with zinc oxide eugenol paste). The 24-h postoperative pain, regression time of gingival congestion and redness, clinical efficacy, and incidence of adverse reactions were compared between the groups. Patients were further categorized into the ineffective and effective treatment groups based on clinical efficacy. Logistic multiple regression analysis explored factors affecting the efficacy of pulp capping treatment.
A significant difference in 24-h postoperative pain was observed between the groups ( < 0.05), with a higher proportion of grade I pain noted in the observation group than in the control group ( < 0.01). The regression time of gingival congestion and swelling was lower in the observation group (2.61 ± 1.44 d and 2.73 ± 1.36 d, respectively) than in the control group (3.85 ± 1.47 d and 4.28 ± 1.61 d, respectively) ( < 0.05). The 2-wk postoperative total effective rate was lower in the control group (80.00%) than in the observation group (94.00%) ( < 0.05). The incidence of adverse reactions was not significantly different between the control (14.00%) and observation (12.00%) groups ( > 0.05). The proportion of adrenaline usage was lower ( < 0.05) and that of anaerobic digestion by and was higher in the ineffective treatment group than in the effective treatment group ( < 0.05). Logistic multiple regression analysis revealed adrenaline as a protective factor ( < 0.05) and anaerobic digestion by and as risk factors for pulp capping in reversible pulpitis ( < 0.05).
Adrenaline demonstrated therapeutic efficacy in pulp capping treatment for reversible pulpitis, reducing pain and improving clinical symptoms safely. It is a protective factor for pulp capping, whereas and are risk factors. Targeted measures can be implemented to improve clinical efficacy.
肾上腺素在可逆性牙髓炎患者盖髓治疗中的作用尚不清楚。
探讨肾上腺素在可逆性牙髓炎患者盖髓治疗中的作用。
纳入2020年1月至2021年12月在安徽省界首市人民医院接受治疗的100例可逆性牙髓炎患者。将其分为观察组（n = 50；采用肾上腺素治疗）和对照组（n = 50；采用氧化锌丁香油糊剂治疗）。比较两组术后24小时疼痛情况、牙龈充血红肿消退时间、临床疗效及不良反应发生率。根据临床疗效将患者进一步分为治疗无效组和治疗有效组。采用Logistic多元回归分析探讨影响盖髓治疗疗效的因素。
两组术后24小时疼痛情况有显著差异（P < 0.05），观察组I级疼痛比例高于对照组（P < 0.01）。观察组牙龈充血肿胀消退时间（分别为2.61±1.44天和2.73±1.36天）低于对照组（分别为3.85±1.47天和4.28±1.61天）（P < 0.05）。对照组术后2周总有效率（80.00%）低于观察组（94.00%）（P < 0.05）。对照组（14.00%）和观察组（12.00%）不良反应发生率无显著差异（P > 0.05）。治疗无效组肾上腺素使用比例较低（P < 0.05），而变形链球菌和远缘链球菌的厌氧消化比例高于治疗有效组（P < 0.05）。Logistic多元回归分析显示肾上腺素是一个保护因素（P < 0.05），而变形链球菌和远缘链球菌的厌氧消化是可逆性牙髓炎盖髓治疗的危险因素（P < 0.05）。
肾上腺素在可逆性牙髓炎盖髓治疗中显示出治疗效果，能安全减轻疼痛并改善临床症状。它是盖髓治疗的保护因素，而变形链球菌和远缘链球菌是危险因素。可采取针对性措施提高临床疗效。
