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疑似白喉类毒素和破伤风类毒素(dTdap)加强疫苗诱发的体位性直立性心动过速综合征(POTS)。

Suspected Diphtheria Toxoid and Tetanus Toxoid (dTdap) Booster Vaccine-Induced Postural Orthostatic Tachycardia Syndrome (POTS).

作者信息

Katwaroo Arun R, Chandolu Krishna Mohan, Seecheran Valmiki K, Ramcharan Priya, Seecheran Rajeev V, Giddings Stanley, Bhagwandass Neal, Seecheran Naveen A

机构信息

Internal Medicine, Trinidad Institute of Medical Technology, St. Augustine, TTO.

Public Health, Eastern Regional Health Authority, Sangre Grande, TTO.

出版信息

Cureus. 2024 Jul 7;16(7):e64008. doi: 10.7759/cureus.64008. eCollection 2024 Jul.

Abstract

We describe a case of a 40-year-old South Asian woman who presented with symptoms suggestive of postural orthostatic tachycardia syndrome (POTS) following a diphtheria toxoid and tetanus toxoid (dTdap) booster vaccination administered one week prior. The patient's POTS responded favorably to treatment with low-dose fludrocortisone and ivabradine. Clinicians should maintain a high index of suspicion for POTS as a possible vaccine adverse event (VAE) post-dTdap booster inoculation and be aware of appropriate management strategies.

摘要

我们描述了一例40岁的南亚女性病例,该患者在一周前接种白喉类毒素和破伤风类毒素(dTdap)加强疫苗后,出现了提示体位性直立性心动过速综合征(POTS)的症状。患者的POTS对小剂量氟氢可的松和伊伐布雷定治疗反应良好。临床医生应高度怀疑POTS是dTdap加强接种后可能出现的疫苗不良事件(VAE),并了解适当的管理策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b868/11301768/678f55d295d6/cureus-0016-00000064008-i01.jpg

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本文引用的文献

1
Global epidemiology and burden of tetanus from 1990 to 2019: A systematic analysis for the Global Burden of Disease Study 2019.
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Suspected COVID-19 mRNA Vaccine-Induced Postural Orthostatic Tachycardia Syndrome.
Cureus. 2023 Jan 26;15(1):e34236. doi: 10.7759/cureus.34236. eCollection 2023 Jan.
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Vaccine-Associated Neurological Adverse Events: A Case Report and Literature Review.
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