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临床病例报告:先天性十二指肠狭窄手术期间的新生儿肠系膜牵引综合征

Clinical Case Report: Neonatal Mesenteric Traction Syndrome During Surgery for Congenital Duodenal Stenosis.

作者信息

Kodama Sahoko, Tomiki Maiko, Sato Koji, Ueki Shigeharu, Niiyama Yukitoshi

机构信息

Department of Anesthesiology and Intensive Care Medicine, Akita University Graduate School of Medicine, Akita, JPN.

Department of General Internal Medicine and Clinical Laboratory Medicine, Akita University Graduate School of Medicine, Akita, JPN.

出版信息

Cureus. 2024 Jul 6;16(7):e63994. doi: 10.7759/cureus.63994. eCollection 2024 Jul.

Abstract

Mesenteric traction syndrome (MTS) is a common complication of major abdominal surgery, characterized by flushing, hypotension, and tachycardia. However, its occurrence in neonates has not yet been documented. This report details a neonatal case of MTS that emerged during surgery for congenital duodenal stenosis. The patient was a two-day-old girl, born at 39 weeks and three days of gestation via vaginal delivery, weighing 2708 g. She underwent general anesthesia for the surgery, and continuous IV administration of remifentanil at 0.2 μg/kg/min was commenced minutes before the surgery began. Initially, her arterial pressure was 60-70/40-50 mmHg. However, shortly after bowel manipulation began, her blood pressure rapidly declined to 31/25 mmHg. Concurrently, her heart rate increased from 120 to 170 beats per minute, and she displayed facial and upper body flushing. Arterial blood gas analysis indicated a PaO2 drop from 124 to 61 mmHg at an FiO2 of 0.3. Treatment consisted of infusion loading and two bolus doses of 2.5 μg of phenylephrine (diluted to 2.5 μg/mL), which normalized her blood pressure within approximately 10 minutes. The facial flushing gradually subsided and disappeared after 40 minutes. Subsequent circulatory stability allowed for the successful completion of the surgery. There was no alteration in airway pressure, and hemodynamic stability was only compromised following the commencement of bowel manipulation. Given the serious risks associated with prolonged hemodynamic instability in neonates, the potential for MTS should be considered during anesthetic management in such cases.

摘要

肠系膜牵拉综合征(MTS)是腹部大手术常见的并发症,其特征为面色潮红、低血压和心动过速。然而,新生儿期发生该综合征尚未见文献报道。本报告详细介绍了1例先天性十二指肠狭窄手术期间出现的新生儿MTS病例。患儿为2日龄女童,孕39周+3天经阴道分娩,体重2708 g。手术采用全身麻醉,术前数分钟开始静脉持续输注瑞芬太尼,剂量为0.2 μg/(kg·min)。最初,其动脉压为60 - 70/40 - 50 mmHg。然而,肠道操作开始后不久,其血压迅速降至31/25 mmHg。同时,心率从120次/分钟增至170次/分钟,且出现面部及上身潮红。动脉血气分析显示,在吸入氧分数(FiO2)为0.3时,动脉血氧分压(PaO2)从124 mmHg降至61 mmHg。治疗包括输液负荷及两次推注2.5 μg去氧肾上腺素(稀释至2.5 μg/mL),约10分钟内血压恢复正常。面部潮红在40分钟后逐渐消退并消失。随后的循环稳定使手术得以顺利完成。气道压力无变化,仅在肠道操作开始后血流动力学稳定性受到影响。鉴于新生儿长时间血流动力学不稳定会带来严重风险,此类病例麻醉管理期间应考虑发生MTS的可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/67ea/11300999/151798ae887f/cureus-0016-00000063994-i01.jpg

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