Pandit Aakash Kumar, Pokharel Prajjwal, Sapkota Kabin, Dhakal Sanket, Kurmi Ram Narayan, Ranjan Mukesh Kumar
Department of Gastroenterology and Hepatology Chitwan Medical College Bharatpur Nepal.
Clin Case Rep. 2024 Aug 5;12(8):e9248. doi: 10.1002/ccr3.9248. eCollection 2024 Aug.
This case report describes a 52-year-old patient presenting with recurrent episodes of pancreatitis and renal stones. Further investigation revealed hypocalcemia and elevated parathyroid hormone (PTH) levels, leading to diagnosis of a parathyroid adenoma. This case highlights the importance of considering primary hyperparathyroidism in patients with recurrent pancreatitis and renal stones, as early diagnosis and surgical intervention can prevent recurrence and reduce morbidity.
Primary Hyperparathyroidism secondary to Parathyroid adenoma, rarely presents as acute pancreatitis. A 38-year-young male with a history of recurrent renal stones referred from a local center, presented to the emergency services, with a diagnosis of acute pancreatitis and bilateral renal stones. Laboratory evaluation showed an elevated calcium level, elevated PTH levels, low vitamin D, and low phosphorus levels. CT scan done outside was suggestive of acute pancreatitis along with bilateral renal calculi. USG neck and MIBI scan done as a part of hypercalcemia evaluation showed presence of a right parathyroid adenoma. Parathyroid adenoma was later removed, and calcium and parathyroid levels were normal on subsequent follow ups.
本病例报告描述了一名52岁患者,反复出现胰腺炎和肾结石发作。进一步检查发现低钙血症和甲状旁腺激素(PTH)水平升高,从而诊断为甲状旁腺腺瘤。本病例强调了在反复出现胰腺炎和肾结石的患者中考虑原发性甲状旁腺功能亢进的重要性,因为早期诊断和手术干预可以预防复发并降低发病率。
甲状旁腺腺瘤继发的原发性甲状旁腺功能亢进很少表现为急性胰腺炎。一名38岁的男性,有复发性肾结石病史,从当地中心转诊而来,因急性胰腺炎和双侧肾结石诊断被送往急诊。实验室评估显示钙水平升高、PTH水平升高、维生素D水平低和磷水平低。在外院进行的CT扫描提示急性胰腺炎伴双侧肾结石。作为高钙血症评估的一部分进行的颈部超声检查和甲氧基异丁基异腈扫描显示右侧甲状旁腺腺瘤存在。随后切除了甲状旁腺腺瘤,在后续随访中钙和甲状旁腺水平正常。