Musa Dildar Haji, Sgery Azri Salih Haji, Omar Asaad Shareef, Keorges Gina James, Ibrahim Nashwan Mr
Departments of Surgery.
Pathology, College of Medicine, University of Duhok, Kurdistan Region, Iraq.
Ann Med Surg (Lond). 2023 Jun 28;85(8):4075-4078. doi: 10.1097/MS9.0000000000001005. eCollection 2023 Aug.
Nephrolithiasis, a common urological disease, could indicate a more ominous pathology beyond the kidneys. Patients who present with renal stones must be investigated for serum calcium and subsequently parathyroid hormones, if indicated, as one of the clinical presentations of primary hyperparathyroidism is renal stones.
A 48-year-old married female with a past medical history significant for renal stones presented to the clinic chiefly complaining of muscle pain, joint pain, and fatigue. After thorough investigations, she was diagnosed with a case of primary hyperparathyroidism due to parathyroid adenoma and was managed surgically according to guidelines.
Hypercalcemia, serum calcium of greater than 2 standard deviations above the reference value, is commonly seen to be associated with parathyroid mass therefore, assessment of serum calcium is a necessary step toward the diagnosis of parathyroid adenoma in cases with recurrent renal stones.
Recurrent nephrolithiasis requires more thorough investigation for the possible underlying cause. Primary hyperparathyroidism due to parathyroid adenoma can present with recurrent renal stones and some vague symptoms.
肾结石是一种常见的泌尿系统疾病，可能提示肾脏以外更严重的病变。出现肾结石的患者必须检查血清钙水平，如有必要，随后检查甲状旁腺激素，因为原发性甲状旁腺功能亢进的临床表现之一就是肾结石。
一名48岁已婚女性，既往有肾结石病史，前来诊所就诊，主要抱怨肌肉疼痛、关节疼痛和疲劳。经过全面检查，她被诊断为因甲状旁腺腺瘤导致的原发性甲状旁腺功能亢进，并根据指南进行了手术治疗。
高钙血症，即血清钙高于参考值2个标准差以上，通常与甲状旁腺肿块有关，因此，在复发性肾结石病例中，评估血清钙是诊断甲状旁腺腺瘤的必要步骤。
复发性肾结石需要对可能的潜在病因进行更全面的调查。因甲状旁腺腺瘤导致的原发性甲状旁腺功能亢进可表现为复发性肾结石和一些模糊症状。
