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[恶性淋巴瘤与结核病]

[Malignant lymphoma and tuberculosis].

作者信息

Hörmann K, Garbrecht M

出版信息

Laryngol Rhinol Otol (Stuttg). 1985 Dec;64(12):614-7.

PMID:3910983
Abstract

In 153 patients with malignant lymphoma (1981-1984) one case of simultaneous occurrence of a Non-Hodgkin lymphoma of high grade malignancy and tuberculosis of a cervical lymph node is reported. Typical morphological characteristics were absent. In the first biopsy mycobacterium tuberculosis was demonstrated in a microbiological animal trial. In a second biopsy a centroblastic lymphoma was found. It is possible that the onset of lymph node tuberculosis is promoted by the impaired immunological defence mechanism of the malignant growth. On the other hand, the malignant lymphoma might be caused by the chronic tuberculous inflammation. Independent of this question, a persistent cervical lymphoma must be identified by biopsy and microbiology. An essential factor in deciding both therapy and prognosis of the malignant lymphoma is to diagnose the presence of a tuberculous infection, for the concurrent treatment of primary and secondary disease provides the only chance of cure.

摘要

在153例恶性淋巴瘤患者(1981 - 1984年)中,报告了1例同时发生高度恶性非霍奇金淋巴瘤和颈部淋巴结结核的病例。缺乏典型的形态学特征。在首次活检中,通过微生物动物试验证实了结核分枝杆菌。在第二次活检中发现了中心母细胞性淋巴瘤。恶性肿瘤免疫防御机制受损可能促使淋巴结结核发病。另一方面,恶性淋巴瘤可能由慢性结核性炎症引起。无论这个问题如何,持续性颈部淋巴瘤必须通过活检和微生物学检查来确诊。在决定恶性淋巴瘤的治疗和预后时,一个关键因素是诊断结核感染的存在,因为同时治疗原发性和继发性疾病是治愈的唯一机会。

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