利用转座子相关的 TnpB 在拟南芥和药用植物中的靶向诱变。
Targeted mutagenesis in Arabidopsis and medicinal plants using transposon-associated TnpB.
机构信息
Research and Development Center of Chinese Medicine Resources and Biotechnology, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
Department of Plant Science, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China.
出版信息
J Integr Plant Biol. 2024 Oct;66(10):2083-2086. doi: 10.1111/jipb.13758. Epub 2024 Aug 7.
PMID:39109980
Abstract
The programmable nuclease TnpB is significantly smaller than Cas9, can edit genes in medicinal plants, including Artemisia annua, Salvia miltiorrhiza, Scutellaria baicalensis, Isatis indigotica, and Codonopsis pilosula, and has potential uses in molecular breeding to enhance crop yield and quality.
摘要
可编程核酸酶 TnpB 明显小于 Cas9，可编辑药用植物中的基因，包括青蒿、丹参、黄芩、菘蓝和党参，并且在分子育种中具有提高作物产量和质量的潜在用途。
Zotero 插件