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利用全身代谢模型了解婴儿的代谢。

Understanding the metabolism of infants using whole-body metabolic models.

机构信息

Metabolic and Biomolecular Engineering National Research Laboratory, Department of Chemical and Biomolecular Engineering (BK21 four), Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Republic of Korea; Systems Metabolic Engineering and Systems Healthcare Cross-Generation Collaborative Laboratory, Department of Chemical and Biomolecular Engineering (BK21 four), KAIST, Daejeon 34141, Republic of Korea; KAIST Institute for the BioCentury, KAIST, Daejeon 34141, Republic of Korea; BioProcess Engineering Research Center, KAIST, Daejeon 34141, Republic of Korea; Graduate School of Engineering Biology, KAIST, Daejeon 34141, Republic of Korea.

Metabolic and Biomolecular Engineering National Research Laboratory, Department of Chemical and Biomolecular Engineering (BK21 four), Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Republic of Korea; Systems Metabolic Engineering and Systems Healthcare Cross-Generation Collaborative Laboratory, Department of Chemical and Biomolecular Engineering (BK21 four), KAIST, Daejeon 34141, Republic of Korea.

出版信息

Cell Metab. 2024 Aug 6;36(8):1641-1643. doi: 10.1016/j.cmet.2024.07.001.

DOI:10.1016/j.cmet.2024.07.001
PMID:39111284
Abstract

A whole-body model is a computational representation of sex-specific and organ-resolved whole-body metabolism. In this issue of Cell Metabolism, Zaunseder et al. report whole-body models of infants that represent metabolic, physiological, energetic, and nutritional features, accurately simulating the growth of infants and providing foundations for personalized medicine for infants.

摘要

全身模型是一种针对特定性别和器官的全身代谢的计算表示。在本期《细胞代谢》中,Zaunseder 等人报告了婴儿的全身模型,这些模型代表了代谢、生理、能量和营养特征,能够准确模拟婴儿的生长,并为婴儿的个性化医疗提供基础。

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