Department of Molecular Science and Engineering, National Taipei University of Technology, Taipei, Taiwan; Graduate Institute of Organic and Polymeric Materials, National Taipei University of Technology, Taipei, Taiwan.
Department of Molecular Science and Engineering, National Taipei University of Technology, Taipei, Taiwan; Graduate Institute of Organic and Polymeric Materials, National Taipei University of Technology, Taipei, Taiwan.
Chemosphere. 2024 Sep;364:143028. doi: 10.1016/j.chemosphere.2024.143028. Epub 2024 Aug 5.
The widespread usage of levofloxacin (LVF) intake is executed for several urinary and respiratory systems infections in human. But, its over intake leads to severe damage to humans and the environment by its exposure. Hence the detection of LVF is concerned and we herein developed an electrocatalyst, strontium tungsten oxide nanospheres and later decorated onto the functionalized multiwall carbon nanotubes (SrWO/f-MWCNT) to perform effective electrochemical recognition of LVF in aquatic and biological samples. Binary metal oxide with carbon composite SrWO/f-MWCNT was developed due to its specific features as nanostructures. Various methods of investigation have been examined to identify the physiochemical characteristics like X-ray diffraction, Raman spectroscopy, Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy, and morphological characteristics including field emission scanning electron microscopy, and transmission electron microscopy. The synthesized SrWO/f-MWCNT sample crystalline size was around 32.9 nm. The SrWO/f-MWCNT modified glassy carbon electrode (GCE) has been subjected to electrochemical investigation with a wide linear range of 0.049 μM-574.73 μM with good sensitivity 2.86 μA μM cm, the limit of detection at 14.9 nM for LVF sensing. Furthermore, the designed LVF detection exhibited excellent anti-interference, stability, reproducibility, and repeatability. The as-developed sensor's electrochemical outcomes indicate the superior performance inherent in the developed composite.
左氧氟沙星（LVF）在人类的泌尿系统和呼吸系统感染中被广泛应用。但是，由于其过度摄入，会对人类和环境造成严重的损害。因此，人们关注 LVF 的检测，我们在此开发了一种电催化剂，即锶钨氧化物纳米球，并将其进一步修饰到功能化多壁碳纳米管（SrWO/f-MWCNT）上，以在水相和生物样品中对 LVF 进行有效的电化学识别。由于具有纳米结构等特殊性质，开发了二元金属氧化物与碳复合材料 SrWO/f-MWCNT。采用各种方法对其物理化学特性进行了鉴定，包括 X 射线衍射、拉曼光谱、傅里叶变换红外光谱、X 射线光电子能谱和形貌特征，包括场发射扫描电子显微镜和透射电子显微镜。合成的 SrWO/f-MWCNT 样品的结晶尺寸约为 32.9nm。将 SrWO/f-MWCNT 修饰的玻碳电极（GCE）进行了电化学研究，具有 0.049μM-574.73μM 的宽线性范围和良好的灵敏度 2.86μAμM cm，检测 LVF 的检出限为 14.9nM。此外，设计的 LVF 检测具有出色的抗干扰性、稳定性、重现性和可重复性。所开发传感器的电化学结果表明了所开发复合材料的固有优异性能。
